Introduction: Appropriate care and treatment of a wound is the need of the hour whether it is an infected or a non-infected wound. If wound healing is delayed for some reason, it leads to serious complications and further increases the hospital stay and cost of treatment. Herein, we describe a novel antimicrobial wound dressing formulation (VG111), with an objective to generate the preliminary data showing the distinct advantages in various types of wounds.
Method: This case series involved the treatment of acute cases of wounds or chronic wounds that did not respond well to conventional wound healing treatments with VG111 in patients with different etiologies. Thirteen cases of patients that included patients with diabetes, pressure ulcers, burns, trauma, and others treated with VG111 showed rapid wound healing in all the cases, even obviating the need for a graft when complete skin regeneration occurred.
Result: This was illustrated by clearing of the wound infections, reduction/disappearance of the exudate, appearance of intense granulation, epithelialization, and anti-biofilm activity followed by complete wound closure. This VG111 precludes the need for systemic antimicrobial agents in localized infections and therefore, this single agent is an attempt to address the limitations and the drawbacks of the available products.
Conclusion: Despite patients belonging to the old age group and having comorbidities like diabetes, still VG111 showed effective rapid wound healing, and that too without any scar formation in hardto- heal, infected, and non-infected wounds.
.方法：本病例系列涉及不同病因患者对VG111常规伤口愈合治疗反应不佳的急性伤口或慢性伤口的治疗。13例患者包括糖尿病患者，压疮,烧伤,创伤,在所有情况下，用VG111治疗的其他患者均显示出快速的伤口愈合，甚至在发生完全皮肤再生时无需移植。
结果：通过清除伤口感染来说明，渗出物的减少/消失，强烈造粒的外观，上皮化,和抗生物膜活性，然后完全闭合伤口。这种VG111排除了局部感染对全身抗菌药物的需要，这种单一的代理是试图解决现有产品的局限性和缺点。
结论：尽管患者属于老年组，有糖尿病等合并症，VG111仍然显示出有效的快速伤口愈合，而且在难以治愈的情况下也没有任何疤痕形成，感染,和未感染的伤口。
