关键词: Gastrointestinal motility disorder brain-gut axis electrical stimulation noninvasive neuromodulation vagus nerve

Mesh : Humans Gastrointestinal Diseases / diagnosis therapy Constipation / therapy Gastroparesis / therapy Fecal Incontinence / therapy Gastrointestinal Motility / physiology Transcutaneous Electric Nerve Stimulation / adverse effects methods

来  源:   DOI:10.1080/17474124.2023.2288156   PDF(Pubmed)

Abstract:
UNASSIGNED: Gastrointestinal motility disorders are highly prevalent without satisfactory treatment. noninvasive electrical neuromodulation is an emerging therapy for treating various gastrointestinal motility disorders.
UNASSIGNED: In this review, several emerging noninvasive neuromodulation methods are introduced, including transcutaneous auricular vagal nerve stimulation, percutaneous auricular vagal nerve stimulation, transcutaneous cervical vagal nerve stimulation, transcutaneous electrical acustimulation, transabdominal interference stimulation, tibial nerve stimulation, and translumbosacral neuromodulation therapy. Their clinical applications in the most common gastrointestinal motility are discussed, including gastroesophageal reflux disease, functional dyspepsia, gastroparesis, functional constipation, irritable bowel syndrome, and fecal incontinence. PubMed database was searched from 1995 to June 2023 for relevant articles in English.
UNASSIGNED: Noninvasive neuromodulation is effective and safe in improving both gastrointestinal symptoms and dysmotility; it can be used when pharmacotherapy is ineffective. Future directions include refining the methodology, improving device development and understanding mechanisms of action.
摘要:
胃肠动力障碍是非常普遍的,没有令人满意的治疗。无创神经电调节是治疗各种胃肠动力障碍的新兴疗法。
在这篇评论中,介绍了几种新兴的非侵入性神经调制方法,包括经皮耳廓迷走神经刺激,经皮耳廓迷走神经刺激,经皮颈迷走神经刺激,经皮电刺激,经腹干扰刺激,胫神经刺激,和经腰骶神经调节疗法。讨论了它们在最常见的胃肠蠕动中的临床应用,包括胃食管反流病,功能性消化不良,胃轻瘫,功能性便秘,肠易激综合征,和大便失禁.从1995年到2023年6月,在PubMed数据库中搜索了相关的英文文章。
非侵入性神经调节在改善胃肠道症状和运动障碍方面是有效且安全的;当药物治疗无效时,可以使用它。未来的方向包括完善方法,改善设备开发和理解作用机制。
公众号