关键词: GvHD acute chronic graft-versus-host disease ruxolitinib

Mesh : Humans Bronchiolitis Obliterans Syndrome Consensus Hematopoietic Stem Cell Transplantation Steroids / therapeutic use Nitriles Adrenal Cortex Hormones / therapeutic use Graft vs Host Disease / drug therapy Acute Disease Chronic Disease

来  源:   DOI:10.1111/imj.16255

Abstract:
This position paper provides an overview of the assessment and management of both acute and chronic graft-versus-host disease (GvHD). There is a focus on the use of ruxolitinib, a selective inhibitor of Janus kinase (JAK)1 and JAK2, for the treatment of corticosteroid-refractory and corticosteroid-dependent GvHD.
摘要:
本文概述了急性和慢性移植物抗宿主病(GvHD)的评估和管理。有一个重点是鲁索替尼的使用,Janus激酶(JAK)1和JAK2的选择性抑制剂,用于治疗皮质类固醇难治性和皮质类固醇依赖性GvHD。
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