PDF(Pubmed)
Abstract：
A 60-year-old woman with Hepatitis C infection, cirrhosis, recurrent hepatic hydrothorax, and hepatocellular carcinoma was hospitalized with Coronavirus disease-2019 (COVID-19). After her initial discharge, she was re-admitted three weeks later with decompensated liver disease. Imaging revealed extensive thrombosis in the portal vein, superior mesenteric vein, splenic vein and bilateral brachial veins. Given the acute onset and extent of the thrombosis, the patient received therapeutic anticoagulation despite elevated prothrombin time/ international normalized ratio, thrombocytopenia and low fibrinogen. Cirrhotic patients with COVID-19 maybe at high risk of thrombosis, which can present with significant hepatic decompensation.
摘要：
一名感染丙型肝炎的60岁妇女,肝硬化,复发性肝性胸水,肝细胞癌因2019年冠状病毒病（COVID-19）住院。在她初次出院后,三周后，她因失代偿性肝病再次入院。影像学显示门静脉广泛血栓形成，肠系膜上静脉,脾静脉和双侧肱静脉。鉴于血栓形成的急性发作和程度，尽管凝血酶原时间/国际标准化比率升高，患者仍接受治疗性抗凝治疗，血小板减少和低纤维蛋白原。患有COVID-19的肝硬化患者可能存在血栓形成的高风险，可表现为显著的肝功能失代偿。
