Abstract：
OBJECTIVE: During fat transplantation, adipose tissue is removed from the body and injected into different areas under the skin. The goal of this review article is to look into the efficacy and applicability of fat transplantation in regenerative medicine and rejuvenation, including Nanofat, Microfat, and Millifat.
METHODS: As a search strategy and study selection, we searched the PubMed and Medline databases until 2023 using related keywords (e.g., Nanofat, Microfat and Millifat, Regenerative Medicine, and Rejuvenation).
RESULTS: Autologous fat transplantation has no risk of an allergic reaction or rejection of the transplant by the individual. Autologous adipose tissue is considered an ideal filler for facial rejuvenation and is suggested as the most biocompatible and non-immunogenic skin filler. Adipose tissue transplant may have semi-permanent to permanent effects. According to recent reports, adipose tissues possess a high percentage of mature stem cells. The effect of regenerating adipose tissue and its intrinsic cells can be described as an obvious process. Variations in the sizes of adipose tissues can result in different results depending on the surgical site. Based on topographic assessment, graft fats are assigned depending on the anatomical locations and the size such as Millifat (2-2.5 mm), Microfat (1 mm), and Nanofat (500 μm or less).
CONCLUSIONS: Some characteristics of fat tissue increase its effectiveness, such as increasing stem cells, growth factors, cytokines, and compounds effective in repair, regeneration, and rejuvenation.
METHODS: As a search strategy and study selection, we searched the PubMed and Medline databases until 2023 using related keywords (e.g., Nanofat, Microfat and Millifat, Regenerative Medicine, and Rejuvenation).
RESULTS: Autologous fat transplantation has no risk of an allergic reaction or rejection of the transplant by the individual. Autologous adipose tissue is considered an ideal filler for facial rejuvenation and is suggested as the most biocompatible and non-immunogenic skin filler. Adipose tissue transplant may have semi-permanent to permanent effects. According to recent reports, adipose tissues possess a high percentage of mature stem cells. The effect of regenerating adipose tissue and its intrinsic cells can be described as an obvious process. Variations in the sizes of adipose tissues can result in different results depending on the surgical site. Based on topographic assessment, graft fats are assigned depending on the anatomical locations and the size such as Millifat (2-2.5 mm), Microfat (1 mm), and Nanofat (500 μm or less).
CONCLUSIONS: Some characteristics of fat tissue increase its effectiveness, such as increasing stem cells, growth factors, cytokines, and compounds effective in repair, regeneration, and rejuvenation.
摘要：
目的：在脂肪移植过程中，从体内取出脂肪组织并注射到皮肤下的不同区域。这篇综述文章的目的是研究脂肪移植在再生医学和复兴中的功效和适用性，包括Nanofat,微脂,还有Millifat.
方法：作为搜索策略和研究选择，我们使用相关关键字搜索PubMed和Medline数据库，直到2023年(例如，Nanofat,微脂和Millifat,再生医学,和复兴）。
结果：自体脂肪移植没有个体对移植的过敏反应或排斥反应的风险。自体脂肪组织被认为是面部年轻化的理想填充物，被认为是最具生物相容性和非免疫原性的皮肤填充物。脂肪组织移植可能具有半永久性到永久性的作用。根据最近的报道，脂肪组织具有高比例的成熟干细胞。再生脂肪组织及其固有细胞的作用可以描述为一个明显的过程。取决于手术部位,脂肪组织大小的变化可导致不同的结果。根据地形评估，移植脂肪根据解剖位置和大小分配，如Millifat（2-2.5毫米），微脂肪（1毫米），和Nanofat(500μm或更小)。
结论：脂肪组织的某些特征增加了其有效性，比如增加干细胞，生长因子，细胞因子,和有效修复的化合物，再生,和复兴。
方法：作为搜索策略和研究选择，我们使用相关关键字搜索PubMed和Medline数据库，直到2023年(例如，Nanofat,微脂和Millifat,再生医学,和复兴）。
结果：自体脂肪移植没有个体对移植的过敏反应或排斥反应的风险。自体脂肪组织被认为是面部年轻化的理想填充物，被认为是最具生物相容性和非免疫原性的皮肤填充物。脂肪组织移植可能具有半永久性到永久性的作用。根据最近的报道，脂肪组织具有高比例的成熟干细胞。再生脂肪组织及其固有细胞的作用可以描述为一个明显的过程。取决于手术部位,脂肪组织大小的变化可导致不同的结果。根据地形评估，移植脂肪根据解剖位置和大小分配，如Millifat（2-2.5毫米），微脂肪（1毫米），和Nanofat(500μm或更小)。
结论：脂肪组织的某些特征增加了其有效性，比如增加干细胞，生长因子，细胞因子,和有效修复的化合物，再生,和复兴。
