PDF(Pubmed)
Abstract：
Angiostrongyliasis is a parasitic disease and a leading cause of human eosinophilic meningoencephalitis caused by rat lungworm Angiostrongylus cantonensis. This parasite infects a wide range of animal hosts, including snails and rats, which plays a significant role in zoonotic transmission. The study was conducted to determine the prevalence of A. cantonensis infection in freshwater snails and definitive rat hosts in the agricultural area in Ampayon, Butuan City, Philippines. A total of 54 rat samples and 719 snail individuals were collected in June and July 2020. An overall 2.36% prevalence rate of A. cantonensis snail infection was recorded, consisting of Pomacea canaliculata and Melanoides tuberculata, with a prevalence rate of 4.05% and 1.38%, respectively. Results revealed an overall prevalence of 38.9% in rat infection. Rattus tanezumi (48.48%) showed a higher infection than Rattus norvegicus (23.80%). Higher infection rates were found in rice field environments than residential houses, with 44.12% and 30% prevalence rates, respectively. Moreover, male rats showed higher infection rates (50%) than female rats (26.92%). Among age classes, adult rats had significantly higher infection rates (48.57%) than juvenile rats (21.05%). Correlation analysis showed a significant positive correlation between A. cantonensis infection intensity to the body length (r = 0.603; p = 0.001) and body weight (r = 0.715; p = 0.000) of rats. The study exemplifies the critical role of intermediate and definitive hosts for angiostrongyliasis. Infected freshwater snails and rats in rice fields make these agricultural areas a venue for A. cantonensis emergence. Integrated actions, health education campaigns, surveillance, hygiene, and good farming practices will help prevent the potential risk of the transmission of angiostrongyliasis in the area.
摘要：
管圆线虫病是一种寄生虫病，是由大鼠肺虫广州管圆线虫引起的人类嗜酸性脑膜脑炎的主要原因。这种寄生虫感染多种动物宿主，包括蜗牛和老鼠,在人畜共患传播中起着重要作用。进行这项研究是为了确定A.在安帕永农业地区的淡水蜗牛和确定的大鼠宿主中的广东感染，武端市,菲律宾。在2020年6月和7月共收集了54只大鼠样本和719只蜗牛个体。记录到广东蜗牛感染的总体患病率为2.36％，由Pomaceacanaliculata和Melanoidestuberculata组成，患病率分别为4.05%和1.38%,分别。结果显示，大鼠感染的总体患病率为38.9％。tanezumi鼠（48.48％）的感染率高于nortvegicus鼠（23.80％）。稻田环境中的感染率高于住宅，患病率为44.12%和30%，分别。此外，雄性大鼠的感染率（50％）高于雌性大鼠（26.92％）。在年龄组中，成年大鼠的感染率（48.57％）明显高于幼年大鼠（21.05％）。相关分析显示,感染强度与大鼠体长(r=0.603;p=0.001)和体重(r=0.715;p=0.000)呈显著正相关。该研究举例说明了中间和确定宿主对血管圆线虫病的关键作用。稻田中被感染的淡水蜗牛和老鼠使这些农业区成为广东曲霉出现的场所。综合行动,健康教育运动，监视,卫生,良好的耕作方式将有助于防止该地区传播管圆线虫病的潜在风险。
