Abstract：
Vegetables are crucial for a healthy human diet due to their abundance of essential macronutrients and micronutrients. However, there have been increased reports of antimicrobial-resistant Enterobacteriaceae isolated from vegetables. Enterobacteriaceae is a large group of Gram-negative bacteria that can act as commensals, intestinal pathogens, or opportunistic extraintestinal pathogens. Extraintestinal infections caused by Enterobacteriaceae are a clinical concern due to antimicrobial resistance (AMR). β-lactams have high efficacy against Gram-negative bacteria and low toxicity for eukaryotic cells. These antimicrobials are widely used in the treatment of Enterobacteriaceae extraintestinal infections. This review aimed to conduct a literature survey of the last five years (2018-2023) on the occurrence of β-lactam-resistant Enterobacteriaceae in vegetables. Research was carried out in PubMed, Web of Science, Scopus, ScienceDirect, and LILACS (Latin American and Caribbean Health Sciences Literature) databases. After a careful evaluation, thirty-seven articles were selected. β-lactam-resistant Enterobacteriaceae, including extended-spectrum β-lactamases (ESBLs)-producing, AmpC β-lactamases, and carbapenemases, have been isolated from a wide variety of vegetables. Vegetables are vectors of β-lactam-resistant Enterobacteriaceae, contributing to the dissemination of resistance mechanisms previously observed only in the hospital environment.
摘要：
蔬菜对于健康的人类饮食至关重要，因为它们富含必需的常量营养素和微量营养素。然而,从蔬菜中分离出耐药肠杆菌科细菌的报道越来越多。肠杆菌科是一大批革兰氏阴性菌，可以作为共生菌，肠道病原体，或机会性肠外病原体。由于抗菌素耐药性（AMR），由肠杆菌引起的肠外感染是临床关注的问题。β-内酰胺类对革兰氏阴性菌具有高效力,对真核细胞具有低毒性。这些抗微生物剂广泛用于肠杆菌科肠外感染的治疗。这篇综述旨在对过去五年（2018-2023年）蔬菜中β-内酰胺抗性肠杆菌科的发生进行文献调查。研究是在PubMed进行的，WebofScience,Scopus,ScienceDirect,和LILACS（拉丁美洲和加勒比健康科学文献）数据库。经过仔细评估，选择了37篇文章。β-内酰胺耐药肠杆菌科,包括产超广谱β-内酰胺酶（ESBLs），AmpCβ-内酰胺酶，和碳青霉烯酶,从各种各样的蔬菜中分离出来。蔬菜是β-内酰胺抗性肠杆菌科的载体，有助于以前仅在医院环境中观察到的抗性机制的传播。
