PDF(Pubmed)
Abstract：
We report the case of a 59-year-old female patient, a former smoker, who was diagnosed with bilateral pulmonary nodules. Extensive medical investigations were conducted, including a surgical lung biopsy, which led to the diagnosis of pulmonary amyloidoma. The diagnostic process was guided by the presence of a persistent, polymorphic, and nonspecific clinical picture, strengthened by imaging findings characterized by mixed nodular lesions and the addition of interstitial involvement, along with partial deterioration of the pulmonary parenchyma architecture. Although it is recognized as a benign tumor, pulmonary amyloidoma requires special care in order to rule out systemic involvement, association with lymphomas, or systemic amyloidosis. This case highlights the comprehensive investigations required in the presence of multiple pulmonary nodules and the wide range of possible diagnoses. It underscores the pivotal role of surgical lung biopsy and histopathological examination. The case is instructive, addressing a rare pathology, on the border between specialties, while also emphasizing potential evolving challenges and providing further insights into the clinical course of this disease.
摘要：
我们报道了一个59岁的女性患者，以前的吸烟者，被诊断为双侧肺结节。进行了广泛的医学调查，包括外科肺活检,这导致了肺淀粉样瘤的诊断。诊断过程是由持续存在的，多态,和非特异性临床表现，以混合结节性病变和间质受累为特征的影像学表现得到加强，伴随着肺实质结构的部分恶化。虽然它被认为是良性肿瘤，肺淀粉样瘤需要特别护理以排除全身受累，与淋巴瘤有关，或全身性淀粉样变性.该病例强调了在存在多个肺结节的情况下所需的全面调查以及广泛的可能诊断。它强调了外科肺活检和组织病理学检查的关键作用。这个案子很有启发性,解决一个罕见的病理学，在特色菜之间的边界上，同时还强调了潜在的挑战，并提供了对该疾病临床过程的进一步见解。
