Abstract：
Exosomes are lipid bilayer vesicles, 30-200 nm in diameter, that are produced by cells and play essential roles in cell-cell communication. Exosomes have been studied in several medical fields including dermatology. Hair loss, a major disorder that affects people and sometimes causes mental stress, urgently requires more effective treatment. Because the growth and cycling of hair follicles are governed by interactions between hair follicle stem cells (HFSCs) and dermal papilla cells (DPCs), a better understanding of the mechanisms responsible for hair growth and cycling through exosomes may provide new insights into novel treatments for hair loss. In this review, we focused on the comprehensive knowledge and recent studies on exosomes in the field of hair development and regeneration. We classified exosomes of several cellular origins for the treatment of hair loss. Exosomes and their components, such as microRNAs, are promising drugs for effective hair loss treatment.
摘要：
外泌体是脂质双层囊泡，直径30-200nm，由细胞产生并在细胞间通讯中起重要作用。外泌体已经在包括皮肤病学在内的多个医学领域进行了研究。脱发,一种影响人们的主要疾病，有时会导致精神压力，迫切需要更有效的治疗。因为毛囊的生长和循环是由毛囊干细胞（HFSC）和毛乳头细胞（DPC）之间的相互作用控制的，更好地了解头发生长和通过外泌体循环的机制可能为脱发的新治疗提供新的见解。在这次审查中,我们专注于外泌体在头发发育和再生领域的综合知识和最新研究。我们对几种细胞来源的外泌体进行了分类，以治疗脱发。外泌体及其成分,比如microRNA，是有效治疗脱发的有前途的药物。
