Abstract：
The brain is a remarkably complex organ responsible for a wide range of functions, including the modulation of emotional states and movement. Neuronal circuits are believed to play a crucial role in integrating sensory, cognitive, and emotional information to ultimately guide motor behavior. Over the years, numerous studies employing diverse techniques such as electrophysiology, imaging, and optogenetics have revealed a complex network of neural circuits involved in the regulation of emotional or motor processes. Emotions can exert a substantial influence on motor performance, encompassing both everyday activities and pathological conditions. The aim of this review is to explore how emotional states can shape movements by connecting the neural circuits for emotional processing to motor neural circuits. We first provide a comprehensive overview of the impact of different emotional states on motor control in humans and rodents. In line with behavioral studies, we set out to identify emotion-related structures capable of modulating motor output, behaviorally and anatomically. Neuronal circuits involved in emotional processing are extensively connected to the motor system. These circuits can drive emotional behavior, essential for survival, but can also continuously shape ongoing movement. In summary, the investigation of the intricate relationship between emotion and movement offers valuable insights into human behavior, including opportunities to enhance performance, and holds promise for improving mental and physical health. This review integrates findings from multiple scientific approaches, including anatomical tracing, circuit-based dissection, and behavioral studies, conducted in both animal and human subjects. By incorporating these different methodologies, we aim to present a comprehensive overview of the current understanding of the emotional modulation of movement in both physiological and pathological conditions.
摘要：
大脑是一个非常复杂的器官，负责广泛的功能，包括情绪状态和运动的调节。神经元回路被认为在整合感觉中起着至关重要的作用，认知，和情感信息最终指导运动行为。多年来,许多研究采用不同的技术，如电生理学，成像,光遗传学揭示了一个复杂的神经回路网络，涉及情绪或运动过程的调节。情绪会对运动表现产生重大影响，包括日常活动和病理状况。这篇评论的目的是探索情绪状态如何通过将用于情绪处理的神经回路连接到运动神经回路来塑造运动。我们首先全面概述了不同情绪状态对人类和啮齿动物运动控制的影响。根据行为研究，我们着手识别能够调节运动输出的情绪相关结构，行为和解剖学。参与情绪处理的神经元电路广泛连接到运动系统。这些电路可以驱动情绪行为，对生存至关重要，但也可以持续塑造正在进行的运动。总之,对情感和运动之间复杂关系的研究提供了对人类行为的宝贵见解，包括提高绩效的机会，并有望改善身心健康。这篇综述整合了来自多种科学方法的发现，包括解剖追踪，基于电路的解剖，和行为研究，在动物和人类受试者中进行。通过结合这些不同的方法，我们的目的是全面概述当前对生理和病理条件下运动的情绪调节的理解。
