PDF(Pubmed)
Abstract：
We sought to determine the association between Toxoplasma gondii (T. gondii) infection of the central nervous system and suicide in a sample of decedents in Mexico City. One hundred and forty-seven decedents (87 who committed suicide and 60 who did not commit suicide) were studied. Brain tissues (amygdala and prefrontal cortex) of decedents were examined for the detection of T. gondii using immunohistochemistry. Detection of T. gondii was positive in 7 (8.0%) of the 87 cases (6 found in prefrontal cortex and one in amygdala), and in one (1.7%) of the 60 controls (found in prefrontal cortex) (OR: 5.16; 95% CI: 0.61-43.10; P = 0.14). Results suggest that T. gondii infection in brain is not associated with suicide. Further studies to confirm this finding are needed.
摘要：
我们试图确定弓形虫(T.gondii）在墨西哥城的死者样本中感染中枢神经系统和自杀。研究了147名死者（87名自杀者和60名未自杀者）。使用免疫组织化学检查死者的脑组织（杏仁核和前额叶皮层）以检测弓形虫。87例中7例(8.0%)弓形虫检出阳性(6例在前额叶皮质,1例在杏仁核),在60个对照中的一个（1.7％）（在前额叶皮层中发现）（OR：5.16；95％CI：0.61-43.10；P=0.14）。结果表明，脑内弓形虫感染与自杀无关。需要进一步的研究来证实这一发现。
