PDF(Pubmed)
Abstract：
Recent studies have outlined the emerging role of 68Ga-PSMA-11 PET/CT in the diagnostic algorithm of clear cell renal cell carcinoma (ccRCC). We report a unique intra-patient comparison of bilateral primary ccRCC imaged with 68Ga-PSMA-11 PET/CT. Although both tumors resulted 68Ga-PSMA-11 avid, we found a remarkable discrepancy in uptake intensity between the high grade and the low grade ccRCC. This case confirms previous evidence reporting that SUVmax on 68Ga-PSMA-11 PET/CT could be used to discriminate aggressive high grade from more indolent low grade ccRCC, due to their different endothelial expression of PSMA.
摘要：
最近的研究概述了68Ga-PSMA-11PET/CT在透明细胞肾细胞癌（ccRCC）的诊断算法中的新兴作用。我们报告了用68Ga-PSMA-11PET/CT成像的双侧原发性ccRCC的独特患者内比较。尽管两种肿瘤都导致68Ga-PSMA-11狂热，我们发现高等级和低等级ccRCC的吸收强度存在显着差异。该病例证实了先前的证据报告，68Ga-PSMA-11PET/CT上的SUVmax可用于区分侵袭性高等级和更惰性的低等级ccRCC，由于PSMA的内皮表达不同。
