Abstract：
Corynebacterium striatum (CS) is an emerging micro-organism in diabetic foot infection for which there are currently few studies. The objective was to analyze the risk factors (RF) related to CS osteomyelitis in patients with diabetic foot.
A case-control study was conducted in the Diabetic Foot Unit between 2015 and 2021. Forty-four patients with osteomyelitis due to CS (cases) and 44 patients with osteomyelitis due a different micro-organism (controls) were included.
Peripheral artery disease (OR: 2.8, p = 0.037), atrial fibrillation (OR: 3.7, p = 0.034), ischemic diabetic foot (OR: 3.3, p = 0.020) and previous prolonged antibiotic therapy more than 14 days (OR: 3.4, p = 0.012) were identified as RF for osteomyelitis due to CS. When performing the multivariate analysis antibiotic therapy >14 days was independent RF (OR: 3.46; p = 0.017).
Previous antibiotic therapy received more than 14 days is an independent and statistically significant RF for CS osteomyelitis in patients with diabetic foot.
A case-control study was conducted in the Diabetic Foot Unit between 2015 and 2021. Forty-four patients with osteomyelitis due to CS (cases) and 44 patients with osteomyelitis due a different micro-organism (controls) were included.
Peripheral artery disease (OR: 2.8, p = 0.037), atrial fibrillation (OR: 3.7, p = 0.034), ischemic diabetic foot (OR: 3.3, p = 0.020) and previous prolonged antibiotic therapy more than 14 days (OR: 3.4, p = 0.012) were identified as RF for osteomyelitis due to CS. When performing the multivariate analysis antibiotic therapy >14 days was independent RF (OR: 3.46; p = 0.017).
Previous antibiotic therapy received more than 14 days is an independent and statistically significant RF for CS osteomyelitis in patients with diabetic foot.
摘要：
目的：纹状体棒状杆菌（CS）是一种新兴的糖尿病足感染微生物，目前对其研究较少。目的是分析糖尿病足患者CS骨髓炎的危险因素（RF）。
方法：2015年至2021年在糖尿病足单位进行了病例对照研究。包括44例因CS引起的骨髓炎患者（病例）和44例因不同微生物引起的骨髓炎患者（对照）。
结果：外周动脉疾病（OR：2.8，p=0.037），心房颤动（OR：3.7，p=0.034），缺血性糖尿病足(OR:3.3,p=0.020)和既往长期抗生素治疗超过14天(OR:3.4,p=0.012)被确定为CS引起的骨髓炎的RF.当进行多变量分析时,>14天的抗生素治疗是独立的RF(OR:3.46;p=0.017)。
结论：先前接受超过14天的抗生素治疗是糖尿病足患者CS骨髓炎的独立且具有统计学意义的RF。
方法：2015年至2021年在糖尿病足单位进行了病例对照研究。包括44例因CS引起的骨髓炎患者（病例）和44例因不同微生物引起的骨髓炎患者（对照）。
结果：外周动脉疾病（OR：2.8，p=0.037），心房颤动（OR：3.7，p=0.034），缺血性糖尿病足(OR:3.3,p=0.020)和既往长期抗生素治疗超过14天(OR:3.4,p=0.012)被确定为CS引起的骨髓炎的RF.当进行多变量分析时,>14天的抗生素治疗是独立的RF(OR:3.46;p=0.017)。
结论：先前接受超过14天的抗生素治疗是糖尿病足患者CS骨髓炎的独立且具有统计学意义的RF。
