Abstract：
BACKGROUND: The aim of this study is to evaluate and compare erection function (EF) after Excision and Primary Anastomosis Urethroplasty (EPAU) and Buccal Mucosal Graft Urethroplasty (BMGU) in bulbar urethral stricture.
METHODS: Patients who underwent urethroplasty were identified retrospectively. The criteria for inclusion in the study were determined as being over 18 years old and under 70 years old, being sexually active. Exclusion criteria are; preoperative severe erectile dysfunction, stricture outside the bulbar urethra, psychosocial incompatibility, urethral stricture related to pelvic fracture, follow-up time less than a year. As the primary endpoint, the International Index of Erectile Function-5 (IIEF-5) was determined as a comparison of EF in the preoperative and third, sixth and twelfth months after surgery. The secondary endpoint was the evaluation of the effects of demographic data, stricture and treatment characteristics on EF.
RESULTS: Fifty patients were identified considering the inclusion/exclusion criteria. It was observed that there were 30 patients who underwent EPAU and 20 patients who underwent BMGU. At the third month after surgery, EF showed a statistically significant decrease in the EPAU group. In both patient groups, it was observed that the early negative effects after the operation in EF started to improve in the sixth month and returned to the baseline level by the first year.
CONCLUSIONS: EPAU and BMGU techniques have a similar effect on EF in the medium and long term. Both methods can be used safely and effectively in the appropriate patient group.
METHODS: Patients who underwent urethroplasty were identified retrospectively. The criteria for inclusion in the study were determined as being over 18 years old and under 70 years old, being sexually active. Exclusion criteria are; preoperative severe erectile dysfunction, stricture outside the bulbar urethra, psychosocial incompatibility, urethral stricture related to pelvic fracture, follow-up time less than a year. As the primary endpoint, the International Index of Erectile Function-5 (IIEF-5) was determined as a comparison of EF in the preoperative and third, sixth and twelfth months after surgery. The secondary endpoint was the evaluation of the effects of demographic data, stricture and treatment characteristics on EF.
RESULTS: Fifty patients were identified considering the inclusion/exclusion criteria. It was observed that there were 30 patients who underwent EPAU and 20 patients who underwent BMGU. At the third month after surgery, EF showed a statistically significant decrease in the EPAU group. In both patient groups, it was observed that the early negative effects after the operation in EF started to improve in the sixth month and returned to the baseline level by the first year.
CONCLUSIONS: EPAU and BMGU techniques have a similar effect on EF in the medium and long term. Both methods can be used safely and effectively in the appropriate patient group.
摘要：
背景：这项研究的目的是评估和比较球尿道狭窄的切除和原发性吻合尿道成形术（EPAU）和颊粘膜移植尿道成形术（BMGU）后的勃起功能（EF）。
方法：对接受尿道成形术的患者进行回顾性分析。纳入研究的标准被确定为18岁以上和70岁以下，性活跃。排除标准是；术前严重勃起功能障碍，延髓尿道外狭窄,社会心理不相容，与骨盆骨折有关的尿道狭窄，随访时间不到一年。作为主要端点，国际勃起功能指数-5（IIEF-5）被确定为术前和第三EF的比较，术后6个月和12个月。次要终点是对人口统计数据效果的评估，EF的狭窄和治疗特点。
结果：根据纳入/排除标准确定了50名患者。观察到有30名患者接受了EPAU，有20名患者接受了BMGU。手术后的第三个月,EF在EPAU组中显示出统计学上的显着降低。在两组患者中，据观察，EF手术后的早期负面影响在第六个月开始改善，并在第一年恢复到基线水平。
结论：EPAU和BMGU技术在中长期对EF的影响相似。两种方法都可以在适当的患者组中安全有效地使用。
方法：对接受尿道成形术的患者进行回顾性分析。纳入研究的标准被确定为18岁以上和70岁以下，性活跃。排除标准是；术前严重勃起功能障碍，延髓尿道外狭窄,社会心理不相容，与骨盆骨折有关的尿道狭窄，随访时间不到一年。作为主要端点，国际勃起功能指数-5（IIEF-5）被确定为术前和第三EF的比较，术后6个月和12个月。次要终点是对人口统计数据效果的评估，EF的狭窄和治疗特点。
结果：根据纳入/排除标准确定了50名患者。观察到有30名患者接受了EPAU，有20名患者接受了BMGU。手术后的第三个月,EF在EPAU组中显示出统计学上的显着降低。在两组患者中，据观察，EF手术后的早期负面影响在第六个月开始改善，并在第一年恢复到基线水平。
结论：EPAU和BMGU技术在中长期对EF的影响相似。两种方法都可以在适当的患者组中安全有效地使用。
