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Abstract：
BACKGROUND: Good medication compliance is very important for the prognosis of children with epilepsy. We aimed to evaluate the status and influencing factors of medication compliance in children with epilepsy and to provide insights to the clinical nursing care of children with epilepsy.
METHODS: We selected epileptic children admitted to Children\'s Hospital of Nanjing Medical University from February 1, 2022 to August 31, 2022. Self-designed questionnaire and medication compliance scale were used to evaluate the characteristics and medication compliance of children with epilepsy. Pearson correlation analysis and multivariate logistic regression were used to analyze the influencing factors of medication compliance.
RESULTS: A total of 156 children with epilepsy were included, the incidence of poor compliance in children with epilepsy was 37.18%. Pearson correlation analysis indicated that age(r = 0.622), courses of epilepsy(r = 0.553), parental education level(r = 0.506), monthly household income(r = 0.652) and number of drugs taken(r = 0.577) were correlated with the compliance(all P<0.05). Logistic regression analyses indicated that age ≤ 6 y(OR = 2.104, 95%CI: 1.712 ~ 2.527), courses of epilepsy ≤ 3 years(OR = 2.661, 95%CI: 2.089 ~ 2.941), low parental education level(OR = 1.977, 95%CI: 1.314 ~ 2.351), monthly household income ≤ 5000 RMB(OR = 2.812, 95%CI: 2.194 ~ 3.181), number of drugs taken ≥ 3(OR = 3.025, 95%CI: 2.336 ~ 3.475) were the influencing factors of medication compliance in children with epilepsy(all P<0.05).
CONCLUSIONS: The medication compliance of children with epilepsy needs to be improved, and the medication compliance of children is affected by age, courses of epilepsy, parental education level, monthly household income and number of drugs taken. Clinical medical personnel take targeted nursing measures against these factors to improve the medication compliance of children with epilepsy.
METHODS: We selected epileptic children admitted to Children\'s Hospital of Nanjing Medical University from February 1, 2022 to August 31, 2022. Self-designed questionnaire and medication compliance scale were used to evaluate the characteristics and medication compliance of children with epilepsy. Pearson correlation analysis and multivariate logistic regression were used to analyze the influencing factors of medication compliance.
RESULTS: A total of 156 children with epilepsy were included, the incidence of poor compliance in children with epilepsy was 37.18%. Pearson correlation analysis indicated that age(r = 0.622), courses of epilepsy(r = 0.553), parental education level(r = 0.506), monthly household income(r = 0.652) and number of drugs taken(r = 0.577) were correlated with the compliance(all P<0.05). Logistic regression analyses indicated that age ≤ 6 y(OR = 2.104, 95%CI: 1.712 ~ 2.527), courses of epilepsy ≤ 3 years(OR = 2.661, 95%CI: 2.089 ~ 2.941), low parental education level(OR = 1.977, 95%CI: 1.314 ~ 2.351), monthly household income ≤ 5000 RMB(OR = 2.812, 95%CI: 2.194 ~ 3.181), number of drugs taken ≥ 3(OR = 3.025, 95%CI: 2.336 ~ 3.475) were the influencing factors of medication compliance in children with epilepsy(all P<0.05).
CONCLUSIONS: The medication compliance of children with epilepsy needs to be improved, and the medication compliance of children is affected by age, courses of epilepsy, parental education level, monthly household income and number of drugs taken. Clinical medical personnel take targeted nursing measures against these factors to improve the medication compliance of children with epilepsy.
摘要：
背景：良好的用药依从性对癫痫患儿的预后非常重要。目的探讨癫痫患儿服药依从性现状及影响因素,为癫痫患儿的临床护理提供参考。
方法：选取2022年2月1日至2022年8月31日南京医科大学儿童医院收治的癫痫患儿。采用自行设计的问卷和服药依从性量表对癫痫患儿的特点和服药依从性进行评价。采用Pearson相关分析和多因素logistic回归分析影响服药依从性的因素。
结果：共纳入156例癫痫患儿，癫痫患儿依从性差的发生率为37.18%。皮尔逊相关分析表明，年龄(r=0.622)，癫痫的病程（r=0.553），父母教育水平(r=0.506)，家庭月收入(r=0.652)和服药次数(r=0.577)与依从性相关(均P<0.05)。Logistic回归分析显示年龄≤6岁(OR=2.104,95CI:1.712~2.527),癫痫病程≤3年(OR=2.661,95CI:2.089~2.941),父母受教育程度低(OR=1.977，95CI：1.314~2.351)，家庭月收入≤5000元(OR=2.812，95CI：2.194~3.181)，服药次数≥3次(OR=3.025,95CI:2.336~3.475)是癫痫患儿服药依从性的影响因素(均P<0.05)。
结论：癫痫患儿的用药依从性有待提高，儿童的服药依从性受年龄的影响，癫痫的疗程，父母的教育水平，每月家庭收入和服用药物的数量。临床医务人员针对这些因素采取有针对性的护理措施,以提高癫痫患儿的用药依从性。
方法：选取2022年2月1日至2022年8月31日南京医科大学儿童医院收治的癫痫患儿。采用自行设计的问卷和服药依从性量表对癫痫患儿的特点和服药依从性进行评价。采用Pearson相关分析和多因素logistic回归分析影响服药依从性的因素。
结果：共纳入156例癫痫患儿，癫痫患儿依从性差的发生率为37.18%。皮尔逊相关分析表明，年龄(r=0.622)，癫痫的病程（r=0.553），父母教育水平(r=0.506)，家庭月收入(r=0.652)和服药次数(r=0.577)与依从性相关(均P<0.05)。Logistic回归分析显示年龄≤6岁(OR=2.104,95CI:1.712~2.527),癫痫病程≤3年(OR=2.661,95CI:2.089~2.941),父母受教育程度低(OR=1.977，95CI：1.314~2.351)，家庭月收入≤5000元(OR=2.812，95CI：2.194~3.181)，服药次数≥3次(OR=3.025,95CI:2.336~3.475)是癫痫患儿服药依从性的影响因素(均P<0.05)。
结论：癫痫患儿的用药依从性有待提高，儿童的服药依从性受年龄的影响，癫痫的疗程，父母的教育水平，每月家庭收入和服用药物的数量。临床医务人员针对这些因素采取有针对性的护理措施,以提高癫痫患儿的用药依从性。
