关键词: gastrointestinal surgery hepatic cancer liver disease

Mesh : Humans Pseudolymphoma / diagnosis pathology Liver Cirrhosis, Biliary / complications diagnosis Liver Neoplasms / diagnosis Lymphadenopathy Cholangitis

来  源:   DOI:10.1136/bcr-2023-254963   PDF(Pubmed)

Abstract:
Hepatic reactive lymphoid hyperplasia is an uncommon benign condition, often found incidentally as a solitary liver lesion. The chronic inflammatory reaction associated with autoimmune conditions and malignancies has been postulated as a possible aetiology. The diagnosis is challenging as it often mimics various malignancies radiologically and histologically, hence the diagnosis being made only after surgical resection. Lymphadenopathy is common with primary biliary cholangitis, though rarely reported with reactive lymphoid hyperplasia. We report a case of hepatic reactive lymphoid hyperplasia associated with portacaval lymphadenopathy in a patient with primary biliary cholangitis, diagnosed after surgical resection. We propose lesional biopsy be considered in patients with primary biliary cholangitis found to have a solitary lesion with supporting low-risk clinical and radiological features.
摘要:
肝反应性淋巴增生是一种罕见的良性疾病,常被偶然发现为孤立的肝脏病变。与自身免疫性疾病和恶性肿瘤相关的慢性炎症反应已被假定为可能的病因。诊断具有挑战性,因为它通常在放射学和组织学上模仿各种恶性肿瘤,因此,只有在手术切除后才能做出诊断。淋巴结肿大常见于原发性胆汁性胆管炎,尽管很少报道有反应性淋巴增生。我们报告了一例原发性胆汁性胆管炎患者与门腔淋巴结肿大相关的肝反应性淋巴增生,手术切除后诊断。我们建议在发现具有孤立性病变并支持低风险临床和放射学特征的原发性胆汁性胆管炎患者中考虑病灶活检。
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