Abstract：
Sulfur is essential in the inception of life and crucial for maintaining human health. This mineral is primarily supplied through the intake of proteins and is used for synthesizing various sulfur-containing biomolecules. Recent research has highlighted the biological significance of endogenous supersulfides, which include reactive persulfide species and sulfur catenated residues in thiol and proteins. Ingestion of exogenous sulfur compounds is essential for endogenous supersulfide production. However, the content and composition of supersulfides in foods remain unclear. This study investigated the supersulfide profiles of protein-rich foods, including edible animal meat and beans. Quantification of the supersulfide content revealed that natto, chicken liver, and bean sprouts contained abundant supersulfides. In general, the supersulfide content in beans and their derivatives was higher than that in animal meat. The highest proportion (2.15 %) was detected in natto, a traditional Japanese fermented soybean dish. These results suggest that the abundance of supersulfides, especially in foods like natto and bean sprouts, may contribute to their health-promoting properties. Our findings may have significant biological implications and warrant developing novel dietary intervention for the human health-promoting effects of dietary supersulfides abundantly present in protein-rich foods such as natto and bean sprouts.
摘要：
硫是生命开始时必不可少的，对维持人类健康至关重要。这种矿物质主要通过蛋白质的摄入提供，用于合成各种含硫的生物分子。最近的研究强调了内源性过硫化物的生物学意义，其中包括硫醇和蛋白质中的反应性过硫化物和硫连接残基。外源性硫化合物的摄入对于内源性超硫化物的产生是必不可少的。然而,食品中超硫化物的含量和组成尚不清楚。这项研究调查了富含蛋白质的食物的超硫化物概况，包括可食用的动物肉和豆类。超硫化物含量的定量显示纳豆，鸡肝,豆芽含有丰富的超硫化物。总的来说,豆类及其衍生物中的超硫化物含量高于动物肉。纳豆中检出比例最高(2.15%),一种传统的日本发酵大豆菜。这些结果表明，丰富的超硫化物，尤其是像纳豆和豆芽这样的食物，可能有助于他们的健康促进特性。我们的发现可能具有重要的生物学意义，并需要开发新型的饮食干预措施，以促进纳豆和豆芽等富含蛋白质的食物中大量存在的饮食超硫化物对人类健康的促进作用。
