PDF(Pubmed)
Abstract：
The incidence of gliomas is approximately 3-5/100,000, with high-grade gliomas accounting for approximately 30-40% of these tumors. Surgery is a confirmed positive factor in prolonging the survival of these patients, and a larger resection range means a longer survival time. Therefore, surgery for high-grade glioma patients should aim to maximize the extent of resection while preserving neurological function to achieve a better quality of life. There is consensus regarding the need to lengthen progression-free survival (PFS) and overall survival (OS) times. In glioma surgery, methods such as intraoperative computed tomography (ICT), intraoperative magnetic resonance imaging (IMRI), navigation, 5-aminolevulinic acid (5-ALA), and intraoperative ultrasound (IOUS) are used to achieve an expanded resection during the surgical procedure. IOUS has been increasingly used in the surgery of high-grade gliomas and various tumors due to its convenient intraoperative use, its flexible repeatability, and the relatively low cost of operating room construction. With the continuous upgrading of ultrasound equipment, IOUS has been able to better assist surgeons in achieving an increased extent of resection. This review aims to summarize the application of ultrasound in the surgery of high-grade gliomas in the past decade, its improvement in patient prognosis, and its prospects.
摘要：
神经胶质瘤的发病率约为3-5/100,000,其中高级别神经胶质瘤约占这些肿瘤的30-40%。手术是延长这些患者生存期的一个明确的积极因素，更大的切除范围意味着更长的存活时间。因此,高级别胶质瘤患者的手术应在保留神经功能的同时，最大限度地扩大手术切除范围，以获得更好的生活质量。对于延长无进展生存期(PFS)和总生存期(OS)时间的必要性存在共识。在神经胶质瘤手术中，方法，如术中计算机断层扫描（ICT），术中磁共振成像（IMRI），导航,5-氨基乙酰丙酸（5-ALA），术中超声（IOUS）用于在手术过程中实现扩大切除。由于术中使用方便,IOUS越来越多地应用于高级别胶质瘤和各种肿瘤的手术中,其灵活的可重复性，和相对较低的手术室建设成本。随着超声设备的不断升级，IOUS已经能够更好地帮助外科医生实现更大程度的切除。本文就近十年来超声在高级别胶质瘤手术中的应用作一综述。改善患者预后，和它的前景。
