PDF(Pubmed)
Abstract：
BACKGROUND: Cancer case during pregnancy is rare, but it is the second leading cause of maternal mortality.
METHODS: A-32-year old pregnant woman with a gestational age of 37 weeks was admitted to the hospital due to repeated coughing for 5 months. She received Veno-Venous Extracorporeal Membrane Oxygenation (V-V ECMO) treatment for severe hypoxemia after delivery. She was diagnosed with non-small cell lung cancer (NSCLC) with bone metastasis and pneumocystis pneumonia (PCP). She subsequently received anti-tumor therapy and anti-infective therapy. After treatment, her condition improved and she was weaned from ECMO. Two weeks after weaning ECMO, her condition worsened again. Her family chose palliative treatment, and she ultimately died.
CONCLUSIONS: NSCLC is rare during pregnancy. At present, there is still a lack of standardized methods to manage these cases. For theses cases, the clinician should be wary of opportunistic infections, such as pneumocystis jirovecii (P. jirovecii) and Elizabethkingia spp. Specialized medical teams with abundant experience and multidisciplinary discussions from the perspectives of the patient\'s clinical characteristics as well as preferences are crucial for developing individualized and the best approach.
METHODS: A-32-year old pregnant woman with a gestational age of 37 weeks was admitted to the hospital due to repeated coughing for 5 months. She received Veno-Venous Extracorporeal Membrane Oxygenation (V-V ECMO) treatment for severe hypoxemia after delivery. She was diagnosed with non-small cell lung cancer (NSCLC) with bone metastasis and pneumocystis pneumonia (PCP). She subsequently received anti-tumor therapy and anti-infective therapy. After treatment, her condition improved and she was weaned from ECMO. Two weeks after weaning ECMO, her condition worsened again. Her family chose palliative treatment, and she ultimately died.
CONCLUSIONS: NSCLC is rare during pregnancy. At present, there is still a lack of standardized methods to manage these cases. For theses cases, the clinician should be wary of opportunistic infections, such as pneumocystis jirovecii (P. jirovecii) and Elizabethkingia spp. Specialized medical teams with abundant experience and multidisciplinary discussions from the perspectives of the patient\'s clinical characteristics as well as preferences are crucial for developing individualized and the best approach.
摘要：
背景：怀孕期间的癌症病例很少见，但它是孕产妇死亡的第二大原因。
方法：A-32岁、胎龄37周的孕妇因反复咳嗽5个月入院。她在分娩后接受了静脉-静脉体外膜氧合（V-VECMO）治疗，以治疗严重的低氧血症。她被诊断为患有骨转移和肺囊虫肺炎（PCP）的非小细胞肺癌（NSCLC）。随后她接受了抗肿瘤治疗和抗感染治疗。治疗后,她的病情好转，她从ECMO断奶。ECMO断奶两周后，她的病情再次恶化。她的家人选择了姑息治疗，她最终死了.
结论：非小细胞肺癌在妊娠期间是罕见的。目前,仍然缺乏管理这些案件的标准化方法。对于这些情况，临床医生应该警惕机会性感染，如肺囊虫(P.jirovecii）和Elizabethkingiaspp。具有丰富经验的专业医疗团队以及从患者临床特征和偏好的角度进行多学科讨论对于制定个性化和最佳方法至关重要。
方法：A-32岁、胎龄37周的孕妇因反复咳嗽5个月入院。她在分娩后接受了静脉-静脉体外膜氧合（V-VECMO）治疗，以治疗严重的低氧血症。她被诊断为患有骨转移和肺囊虫肺炎（PCP）的非小细胞肺癌（NSCLC）。随后她接受了抗肿瘤治疗和抗感染治疗。治疗后,她的病情好转，她从ECMO断奶。ECMO断奶两周后，她的病情再次恶化。她的家人选择了姑息治疗，她最终死了.
结论：非小细胞肺癌在妊娠期间是罕见的。目前,仍然缺乏管理这些案件的标准化方法。对于这些情况，临床医生应该警惕机会性感染，如肺囊虫(P.jirovecii）和Elizabethkingiaspp。具有丰富经验的专业医疗团队以及从患者临床特征和偏好的角度进行多学科讨论对于制定个性化和最佳方法至关重要。
