关键词: Diabetic Striatopathy (DS) MR spectroscopy hemichorea/hemiballism movement disorders

Mesh : Male Humans Aged Hyperglycemia / complications diagnosis Dyskinesias / diagnostic imaging etiology Chorea / diagnostic imaging etiology Magnetic Resonance Imaging Magnetic Resonance Spectroscopy / adverse effects

来  源:   DOI:10.1111/cpf.12865

Abstract:
BACKGROUND: Diabetic Striatopathy (DS) is a rare complication of a poor-controlled Diabetes Mellitus consisting of sudden onset of movement disorders. To date, there is still poor knowledge about the pathogenesis.
METHODS: We describe a 79 year old men affected by sudden onset hemichoreic movements whose cause was a non-ketotic hyperglycaemia diagnosed despite the normal blood glucose levels thanks to brain CT and magnetic resonance imaging. Then, we introduce a new magnetic resonance spectroscopy (MRS) finding never described until today which allowed us to produce a new pathogenetic theory of a phenomenon still without definitive explanations.
METHODS: We performed a review of DS cases using the Medline database and we extracted main data regarding imaging findings.
CONCLUSIONS: Thanks to our MRS we show new imaging findings never described until today, with a new pathogenetic explanation, since all the causative hypotheses produced during the past years have never found evidence.
摘要:
背景:糖尿病性纹状体病(DS)是控制不良的糖尿病的罕见并发症,包括突然发作的运动障碍。迄今为止,对发病机理仍然知之甚少。
方法:我们描述了一名79岁的男性,其原因是突然发作的半红细胞运动,尽管由于脑部CT和磁共振成像的血糖水平正常,但诊断为非酮症性高血糖。然后,我们介绍了一种直到今天才被描述的新的磁共振波谱(MRS)发现,这使我们能够产生一种仍然没有明确解释的现象的新致病理论。
方法:我们使用Medline数据库对DS病例进行了回顾,并提取了有关影像学发现的主要数据。
结论:由于我们的MRS,我们显示了直到今天才描述的新影像学发现,有了新的致病解释,因为过去几年产生的所有因果假设都没有找到证据。
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