PDF(Pubmed)
Abstract：
Endometriosis, a prevalent disorder in women of reproductive age, is often associated with undesired infertility. Ovarian reserve, an essential measure of ovarian function that is crucial for maintaining fecundity, is frequently diminished in women with endometriosis. Though the causative relationship between endometriosis and reduced ovarian reserve is not fully understood due to the lack of standardized and precise measurements of ovarian reserve, there is ongoing discussion regarding the impact of interventions for endometriosis on ovarian reserve. Therefore, in this review, we investigate articles that have related keywords and which were also published in recent years. Thereafter, we provide a comprehensive summary of evidence from in vitro, in vivo, and human studies, thereby shedding light on the decreased ovarian reserve in endometriosis. This research consolidates evidence from in vitro, in vivo, and human studies on the diminished ovarian reserve associated with endometriosis, as well as enhances our understanding of whether and how endometriosis, as well as its interventions, contribute to reductions in ovarian reserve. Furthermore, we explore potential strategies to modify existing therapy options that could help prevent diminished ovarian reserve in patients with endometriosis.
摘要：
子宫内膜异位症,育龄妇女普遍存在的疾病，通常与不希望的不孕症有关。卵巢储备,卵巢功能的一项重要指标，对维持生育力至关重要，在子宫内膜异位症女性中经常减少。虽然子宫内膜异位症和卵巢储备功能降低之间的因果关系尚未完全了解，由于缺乏标准化和精确测量卵巢储备功能，关于子宫内膜异位症干预措施对卵巢储备的影响,目前正在进行讨论.因此,在这次审查中,我们调查有相关关键词的文章，这些文章也是在最近几年发表的。此后,我们提供了来自体外的证据的全面总结，在体内，和人类研究，从而揭示子宫内膜异位症卵巢储备功能下降。这项研究巩固了体外的证据，在体内，和关于子宫内膜异位症相关卵巢储备减少的人类研究，以及增强我们对子宫内膜异位症的理解，以及它的干预，有助于减少卵巢储备。此外，我们探索修改现有治疗方案的潜在策略,这些治疗方案有助于预防子宫内膜异位症患者卵巢储备减少.
