Abstract:
Bartholin gland carcinoma is an extremely rare disease. Information regarding treatment is scarce and there is no strict consensus on best practice. All studies reporting cases of Bartholin\'s gland cancer were screened and evaluated for inclusion. Baseline characteristics of studies were extracted. A total number of 290 manuscripts collected were available for the review process. Studies included in a previous systematic review were not duplicated. In total, details of 367 patients were collected, as follows: histological features, clinical presentation, treatment, recurrent rate, treatment of recurrence and outcome. About 35% of Bartholin gland carcinoma were squamous cell carcinoma. Almost 50% of patients presented with advanced stage. The therapeutic approach was mainly surgery, and in 61% of those women lymph node assessment was performed. Recurrence occurred in 21% of cases. Bartholin gland cancer remains a challenge for gynecologic oncologists. Guidelines, centralization to referral centers and standardized therapy are needed.
摘要:
Bartholin腺癌是一种极其罕见的疾病。有关治疗的信息很少,并且在最佳实践方面没有严格的共识。所有报告Bartholin腺体癌病例的研究均进行筛选和评估。提取研究的基线特征。总共收集了290份手稿,可用于审查过程。以前的系统评价中包含的研究没有重复。总的来说,收集了367名患者的详细信息,如下:组织学特征,临床表现,治疗,复发率,治疗复发和结果。约35%的Bartholin腺癌为鳞状细胞癌。近50%的患者出现晚期。治疗方法主要是手术,61%的女性进行了淋巴结评估。21%的病例复发。Bartholin腺癌仍然是妇科肿瘤学家的挑战。指导方针,需要集中到转诊中心和标准化治疗。