PDF(Pubmed)
Abstract：
We focus on reviewing state-of-the-art developments of dedicated PET scanners with irregular geometries and the potential of different aspects of multifunctional PET imaging. First, we discuss advances in non-conventional PET detector geometries. Then, we present innovative designs of organ-specific dedicated PET scanners for breast, brain, prostate, and cardiac imaging. We will also review challenges and possible artifacts by image reconstruction algorithms for PET scanners with irregular geometries, such as non-cylindrical and partial angular coverage geometries and how they can be addressed. Then, we attempt to address some open issues about cost/benefits analysis of dedicated PET scanners, how far are the theoretical conceptual designs from the market/clinic, and strategies to reduce fabrication cost without compromising performance.
摘要：
我们专注于回顾具有不规则几何形状的专用PET扫描仪的最新发展以及多功能PET成像的不同方面的潜力。首先,我们讨论了非常规PET探测器几何形状的进展。然后，我们提出了针对乳房的器官专用PET扫描仪的创新设计，大脑,前列腺,和心脏成像。我们还将回顾不规则几何形状的PET扫描仪的图像重建算法的挑战和可能的伪影，例如非圆柱形和部分角度覆盖几何形状以及如何解决它们。然后，我们试图解决一些关于专用PET扫描仪的成本/收益分析的公开问题，理论概念设计离市场/诊所有多远，以及在不影响性能的情况下降低制造成本的策略。
