Abstract：
In this study we proposed to address the following question: \"Are there differentially expressed sperm microRNAs related to fertility in bulls?\". A systematic review of scientific literature until November 2022 was performed, in accordance with PRISMA guidelines. The main outcome was differentially expressed sperm microRNA from bulls with low versus high fertility profiles identified by using different methods such as field fertility evaluation and sperm laboratory analysis. Were identified 786 documents, of which 13 were selected for qualitative analysis. A total of 182 unique differentially expressed miRNAs were identified, among these, 49 miRNAs were found in common between at least two studies. It is believed that from these 49 miRNAs, it is possible that miRNAs such as miR-10a, -10b, -103, -15b, -122, -125b, -126-5p, -151-5p, -193a-5p, -196a, -27a-5p and -99b could be potential universal biomarkers to assess the reproductive potential of males.
摘要：
在这项研究中，我们提出解决以下问题：“是否存在与公牛生育力相关的差异表达精子microRNAs？”对2022年11月之前的科学文献进行了系统的审查，按照PRISMA准则。主要结果是通过使用不同的方法（例如田间生育力评估和精子实验室分析）鉴定的具有低生育力和高生育力的公牛的精子microRNA的差异表达。已确认786份文件，其中选择13个进行定性分析。总共鉴定了182个独特的差异表达的miRNA，其中,在至少两项研究之间共同发现了49种miRNA。据认为，从这49个miRNAs，miRNAs如miR-10a，-10b,-103，-15b，-122，-125b，-126-5p，-151-5p，-193a-5p，196a，-27a-5p和-99b可能是评估男性生殖潜力的潜在通用生物标志物。
