关键词: antibacterial cerium oxide nanoparticles rare-earth elements wound healing

Mesh : Anti-Bacterial Agents / pharmacology Antioxidants / pharmacology Bandages Nanoparticles Wound Healing Cerium / pharmacology

来  源:   DOI:10.1002/adhm.202302858

Abstract:
Cerium (Ce) is a hot topic in the field of materials research due to its electronic layer structure and the unique antioxidant abilities of its oxide (CeO2 ). Cerium oxide nanoparticles (CeO2 NPs) demonstrate their potential as an antioxidant and antibacterial agent. Current research focuses on whether they can be used to promote wound healing and in what manner. This article provides a systematic review of the various forms of CeO2 NPs that are used in wound-healing materials over the past decade, as well as the effectiveness demonstrated by in vivo and in vitro experiments, with a focus on the relationship between concentration and effectiveness. CeO2 NPs are expected to become effective ingredients in dressings that require antibacterial, antioxidant, and wound healing promoting properties. This article serves as a reference for further research and clinical applications of nano-sized CeO2 in wound healing.
摘要:
铈(Ce)因其电子层结构及其氧化物(CeO2)独特的抗氧化能力而成为材料研究领域的热点。氧化铈纳米颗粒(CeO2NPs)显示出它们作为抗氧化剂和抗菌剂的潜力。目前的研究集中在它们是否可以用于促进伤口愈合以及以何种方式。本文对过去十年来用于伤口愈合材料的各种形式的CeO2NPs进行了系统的回顾,以及体内和体外实验证明的有效性,专注于浓度和有效性之间的关系。CeO2NPs有望成为需要抗菌的敷料中的有效成分,抗氧化剂,和促进伤口愈合的特性。本文为纳米CeO2在创面愈合中的进一步研究和临床应用提供参考。
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