关键词: asymptomatic gouty tophi gout head and neck region thyroid cartilage

来  源:   DOI:10.1177/01455613231205540

Abstract:
Gouty tophi is a disease characterized by the long-term deposition of monosodium urate crystals in joints or cartilages. The most commonly affected site is the first metatarsophalangeal joint, and gouty tophi in the head and neck region are relatively rare. This article reports a case involving an elderly male with asymptomatic gouty tophi in the thyroid cartilage. The patient had a history of gout for over 10 years and presented with a painless thyroid mass that had been present for at least 3 years. He had not received systemic treatment. Preoperative contrast-enhanced cervical CT results indicated a high likelihood of gouty tophi. Postoperative pathology confirmed the mass to be consistent with gouty nodules. Following the procedure, the patient was treated symptomatically with non-busulfan tablets and colchicine. No recurrence was observed at the 1-year follow-up. This report highlights the need to consider gouty tophi in cases of prolonged gout history and abnormal imaging findings in the head and neck region. Appropriate management, including urate-lowering therapy and surgery, if necessary, can lead to optimal outcomes and prevent recurrences. Further research is warranted to enhance understanding and clinical management of this uncommon regional manifestation of gout.
摘要:
痛风痛风石是一种疾病,其特征在于尿酸单钠晶体在关节或软骨中的长期沉积。最常见的受累部位是第一跖趾关节,头部和颈部痛风痛风石相对罕见。本文报道一例老年男性甲状腺软骨无症状痛风痛风石。患者有10年以上的痛风病史,并出现无痛性甲状腺肿块,至少3年。他没有接受过全身治疗。术前对比增强的宫颈CT结果表明痛风痛风石的可能性很高。术后病理证实肿块符合痛风结节。按照程序,患者接受了非白消安片和秋水仙碱的对症治疗。在1年的随访中没有观察到复发。该报告强调,在长期痛风病史和头颈部异常影像学发现的情况下,需要考虑痛风痛风石。适当的管理,包括降尿酸治疗和手术,如有必要,可以导致最佳结果并防止复发。需要进一步的研究以增强对痛风这种罕见的区域表现的理解和临床管理。
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