关键词: amikacin antibiotic resistance imipenem pus

来  源:   DOI:10.4081/jphia.2023.2307   PDF(Pubmed)

Abstract:
The management of postoperative wound infections is a major problem in hospitals due to the frequent ineffectiveness of antibiotic treatment. The objectives of this study are to identify the bacteria responsible for postoperative wound infections and to describe these antibiotic resistances in order to improve the management of these infections. It is a prospective study of 52 bacteriological results of postoperative wounds for a period of six months from January 2021 to June 2021 in the laboratory of the University Hospital of Befelatanana. This study showed 26 (50%) isolates of staphylococci, 17 (32.7%) isolates of enterobacteria, 6 (11.5%) isolates of streptococci and 3 (5.8%) isolates of nonfermenting gram-negatif bacilli. Antibiotic resistance, varies from 0% (vancomycin) to 92.3% (penicillin G) for staphylococci isolates, 0% (imipenem, amikacin) to 94.1% (amoxicillin) for enterobacteria isolates, 0% (vancomycin) to 50% (penicillin G) for streptococci isolates and 33% (imipenem, amikacin) to 100% (cotrimoxazole) for the isolates of nonfermenting gram-negatif bacilli. The knowledge of antibiotic resistance of bacteria responsible for postoperative wound infections allows better patient management.
摘要:
由于抗生素治疗的频繁无效,术后伤口感染的管理是医院中的主要问题。这项研究的目的是确定导致术后伤口感染的细菌并描述这些抗生素耐药性,以改善这些感染的管理。这是一项从2021年1月至2021年6月在Befelatanana大学医院实验室进行的为期六个月的52例术后伤口细菌学结果的前瞻性研究。这项研究显示26(50%)分离的葡萄球菌,肠杆菌17株(32.7%),6株(11.5%)链球菌和3株(5.8%)非发酵革兰氏阴性杆菌。抗生素耐药性,葡萄球菌分离株从0%(万古霉素)到92.3%(青霉素G)不等,0%(亚胺培南,阿米卡星)对肠杆菌分离株的94.1%(阿莫西林),0%(万古霉素)至50%(青霉素G)的链球菌和33%(亚胺培南,阿米卡星)至100%(复方新诺明),用于非发酵革兰氏阴性杆菌的分离株。了解导致术后伤口感染的细菌的抗生素耐药性可以更好地管理患者。
公众号