METHODS: A bloodstream infection caused by a gram-positive bacterium and related to a central venous catheter was identified in an immunocompromised 2-year-old girl. Tsukamurella tyrosinosolvens was identified by modified secA1 sequencing. Antibiotic treatment and removal of the central venous catheter resolved the infection. Inappropriate management of the catheter during an overnight stay outside of the hospital was considered as a possible source of infection.
CONCLUSIONS: SecA1 sequencing may be a useful diagnostic tool in the identification of T. tyrosinosolvens. Providing proper central venous catheter care instructions to patients, their families, and medical staff is important for infection prevention.
方法:在一名免疫功能低下的2岁女孩中发现了由革兰氏阳性菌引起的与中心静脉导管有关的血流感染。通过改良的secA1测序鉴定了酪氨酸酶。抗生素治疗和中心静脉导管的移除解决了感染。在医院外过夜期间导管的不当管理被认为是可能的感染源。
结论:SecA1测序可能是鉴定酪氨酸梭菌的有用诊断工具。为患者提供适当的中心静脉导管护理指导,他们的家人,医务人员对预防感染很重要。