PDF(Pubmed)
Abstract：
The intricate interplay between the immune system and oral health has revealed opportunities for novel therapeutic interventions in dentistry and periodontics. This review article delves into the pivotal role of immunomodulators in orchestrating immune responses within the oral cavity and their applications in managing various oral and periodontal conditions. The oral environment faces many challenges, from microbial infections to tissue injuries, necessitating a precise immune response for optimal oral health maintenance. Characterized by their ability to modulate immune reactions, immunomodulators emerge as versatile tools for maintaining immune equilibrium. This is a comprehensive overview of the mechanisms through which immunomodulators exert their effects, shedding light on their dual role as regulators of both pro-inflammatory and anti-inflammatory pathways. The diverse applications of immunomodulators within dentistry are explored in depth. Immunomodulators exhibit promising outcomes from managing common oral conditions like gingivitis, periodontitis, and oral ulcers to enhancing the integration of dental implants and promoting wound healing post-surgery. This article highlights the various types of immunomodulatory agents utilized in dental practice, elucidating their mechanisms of action, routes of administration, dosages, and potential side effects.
摘要：
免疫系统与口腔健康之间的复杂相互作用揭示了在牙科和牙周病中进行新型治疗干预的机会。这篇综述文章探讨了免疫调节剂在协调口腔内免疫反应中的关键作用，以及它们在管理各种口腔和牙周疾病中的应用。口腔环境面临许多挑战，从微生物感染到组织损伤，需要精确的免疫反应以维持最佳的口腔健康。以它们调节免疫反应的能力为特征，免疫调节剂是维持免疫平衡的通用工具。这是对免疫调节剂发挥作用的机制的全面概述，阐明了它们作为促炎和抗炎途径调节剂的双重作用。深入研究了免疫调节剂在牙科中的各种应用。免疫调节剂从管理牙龈炎等常见口腔疾病中表现出有希望的结果，牙周炎,和口腔溃疡，以增强牙科植入物的整合并促进术后伤口愈合。本文重点介绍了牙科实践中使用的各种类型的免疫调节剂，阐明它们的作用机制，管理路线,剂量,和潜在的副作用。
