Abstract:
Cerebellar ataxia in adults is always a diagnostic challenge. One of the important causes of late-onset cerebellar ataxia is hypomagnesemia. Hypomagnesemia can have varied manifestations and is attributable to numerous causes. Identification of hypomagnesemia-induced cerebellar syndrome (HiCS) is important as it is reversible but often missed. HiCS has distinct clinical findings and characteristic magnetic resonance imaging (MRI) findings. HiCS presents with distinct clinical, biochemical, and neuroimaging findings, but it cannot be ruled out even in the absence of neuroimaging findings. This condition has to be treated promptly and meticulously to avoid precipitating any serious complications, and a strong suspicion is required for the diagnosis. The underlying cause should be evaluated and managed, as HiCS is a serious but potentially reversible disease with a good prognosis. We present a case of HiCS presenting with a characteristic history of recurrent ataxia, tremor, and vertigo that improved with treatment. Our patient was atypical, as there were no significant MRI findings attributable to hypomagnesemia. Only seven case reports are available throughout the world that show such disparity.
摘要:
成人小脑共济失调始终是诊断挑战。迟发性小脑共济失调的重要原因之一是低镁血症。低镁血症可以有多种表现,可归因于多种原因。HiCS(低镁血症诱导的小脑综合征)的鉴定很重要,因为它是可逆的,但经常被错过。HiCS具有独特的临床发现和特征性的磁共振成像(MRI)发现。HiCS具有明显的临床表现,生物化学,和神经影像学发现,但即使没有神经影像学检查结果也不能排除。这种情况必须得到及时和细致的治疗,以避免引发任何严重的并发症,诊断需要强烈怀疑。应评估和管理根本原因,hiCS是一种严重但潜在可逆的疾病,预后良好。我们介绍了一例HiCS,表现为复发性共济失调的特征性病史,震颤,和眩晕随着治疗而改善。我们的病人不典型,因为没有显著的MRI表现可归因于低镁血症.全世界只有七份病例报告显示出这种差异。