PDF(Pubmed)
Abstract：
Dandy-Walker Syndrome (DWS) is a rare congenital neurological condition characterized by cerebellar and posterior fossa malformations, often presenting a variable clinical spectrum. Common complications include hydrocephalus, necessitating interventions like ventriculoperitoneal (VP) shunts, and endoscopic third ventriculostomy (ETV). We describe the case of a five-month-old infant conceived through in vitro fertilization (IVF), initially presenting with cold-like symptoms, later diagnosed with DWS. The patient underwent VP shunt placement for hydrocephalus management, with subsequent complications requiring shunt revisions and ETV. Vigilant monitoring and timely interventions were crucial for a favorable outcome, highlighting the challenges in diagnosing and managing DWS and the importance of tailored treatment strategies.
摘要：
Dandy-Walker综合征（DWS）是一种罕见的先天性神经系统疾病，其特征是小脑和后颅窝畸形，通常呈现可变的临床频谱。常见的并发症包括脑积水，需要像脑室腹膜（VP）分流术这样的干预措施，和内镜下第三脑室造瘘术（ETV）。我们描述了通过体外受精（IVF）受孕的五个月大婴儿的情况，最初出现类似感冒的症状，后来诊断为DWS。患者接受了VP分流术治疗脑积水，随后的并发症需要分流翻修和ETV。警惕的监测和及时的干预对于取得有利的结果至关重要，强调诊断和管理DWS的挑战以及量身定制的治疗策略的重要性。
