PDF(Pubmed)
Abstract：
Prodromal dementia with Lewy bodies (DLB) refers to a state prior to the onset of dementia with clinical signs or symptoms that may indicate the future development of DLB. Prodromal symptoms can include not only cognitive deficits but also a mix of clinical features including sleep disorders, autonomic dysfunction, and neuro-psychiatric disturbances. While diagnostic criteria for the subtypes of prodromal DLB were recently published, they are largely used in research settings. However, these criteria have important implications for clinical practice. Recognition of prodromal DLB stages can lead to identifying deficits sooner, improved patient and family counseling, and advance care planning. This case series presents examples of the 3 subtypes of prodromal DLB - mild cognitive impairment onset, delirium onset, and psychiatric onset - to help clinicians identify individuals who may be on a trajectory to develop DLB.
摘要：
路易体前驱痴呆(DLB)是指痴呆发作之前的状态,其具有可能指示DLB的未来发展的临床体征或症状。前驱症状不仅包括认知障碍，还包括包括睡眠障碍在内的临床特征。自主神经功能障碍,和神经精神障碍。虽然最近发表了前驱DLB亚型的诊断标准，它们主要用于研究环境。然而,这些标准对临床实践具有重要意义。识别前驱DLB阶段可以导致更快地识别缺陷，改善患者和家庭咨询，和提前护理计划。本病例系列介绍了3种前驱DLB亚型的例子-轻度认知障碍发作，谵妄发作,和精神病发作-帮助临床医生识别可能正在发展DLB的个体。
