Abstract：
UNASSIGNED: The National Pressure Injury Advisory Panel, European Pressure Ulcer Advisory Panel, and the Pan Pacific Pressure Injury Alliance are commencing a new (fourth) edition of the Prevention and Treatment of Pressure Ulcers/Injuries: Clinical Practice Guideline . The fourth edition of the International Pressure Injury (PI) Guideline will be developed using GRADE methods to ensure a rigorous process consistent with evolving international standards. Clinical questions will address prevention and treatment of PIs, identification of individuals at risk of PIs, assessment of skin and tissues, and PI assessment. Implementation considerations supporting application of the guidance in clinical practice will be developed. The guideline development process will be overseen by a guideline governance group and methodologist; the guideline development team will include health professionals, educators, researchers, individuals with or at risk of PIs, and informal carers.This article presents the project structure and processes to be used to undertake a systematic literature search, appraise risk of bias of the evidence, and aggregate research findings. The methods detail how certainty of evidence will be evaluated; presentation of relative benefits, risks, feasibility, acceptability, and resource requirements; and how recommendations will be made and graded. The methods outline transparent processes of development that combine scientific research with best clinical practice. Strong involvement from health professionals, educators, individuals with PIs, and informal carers will enhance the guideline\'s relevance and facilitate uptake. This update builds on previous editions to ensure consistency and comparability, with methodology changes improving the guideline\'s quality and clarity.
摘要：
目标：国家压力伤害咨询小组，欧洲压力性溃疡咨询小组和泛太平洋压力伤害联盟正在开始新的（第四版）压力性溃疡/伤害的预防和治疗：临床实践指南。目的是概述方法。
方法：将使用GRADE方法开发国际PI指南的第四版，以确保严格的流程符合不断发展的国际标准。临床问题将解决PI的预防和治疗，识别有PI风险的个人，皮肤和组织的评估，和PI评估。将制定支持在临床实践中应用指南的实施考虑因素。指南制定过程将由指南治理小组(GGG)和方法学家监督，指南开发团队（GDT）将包括卫生专业人员，教育工作者,研究人员,有或有风险的个人和非正式护理人员。本文介绍了用于进行系统文献检索的项目结构和流程，评估证据偏倚的风险，并汇总研究结果。该方法详细说明了如何评估证据的确定性；相对收益的列报，风险,可行性,可接受性和资源需求以及如何提出建议和分级。
结论：这些方法概述了将科学研究与最佳临床实践相结合的透明开发过程。卫生专业人员的积极参与，教育工作者,具有PI和非正式护理人员的个人将增强指南的相关性并促进吸收。此更新基于以前的版本，以确保一致性和可比性，方法的改变提高了指南的质量和清晰度。
方法：将使用GRADE方法开发国际PI指南的第四版，以确保严格的流程符合不断发展的国际标准。临床问题将解决PI的预防和治疗，识别有PI风险的个人，皮肤和组织的评估，和PI评估。将制定支持在临床实践中应用指南的实施考虑因素。指南制定过程将由指南治理小组(GGG)和方法学家监督，指南开发团队（GDT）将包括卫生专业人员，教育工作者,研究人员,有或有风险的个人和非正式护理人员。本文介绍了用于进行系统文献检索的项目结构和流程，评估证据偏倚的风险，并汇总研究结果。该方法详细说明了如何评估证据的确定性；相对收益的列报，风险,可行性,可接受性和资源需求以及如何提出建议和分级。
结论：这些方法概述了将科学研究与最佳临床实践相结合的透明开发过程。卫生专业人员的积极参与，教育工作者,具有PI和非正式护理人员的个人将增强指南的相关性并促进吸收。此更新基于以前的版本，以确保一致性和可比性，方法的改变提高了指南的质量和清晰度。
