PDF(Pubmed)
Abstract：
UNASSIGNED: Neutrophils are the most common cell types in circulation and are considered the first line of defense in the immune system against microorganisms. This study was undertaken to investigate the occurrence of isolated benign neutropenia (IBN) among healthy individuals in the central region of Saudi Arabia.
UNASSIGNED: This retrospective study analyzed complete blood count tests as part of routine checkups for chronic health conditions from April to September 2022. The 10,442 participants were randomly selected and their medical records were reviewed for neutropenia and mean absolute neutrophil counts (ANCs) were calculated. Descriptive analysis was employed to assess the prevalence of IBN across various demographic factors, such as age, gender, and nationality.
UNASSIGNED: The prevalence of IBN in the central region of Saudi Arabia was found to be 2.82% across the entire cohort of participants. The mean ANC among all participants was 4.55 × 109/L. The prevalence of neutropenia was higher in male participants compared with female. Male neutropenic had a lower mean ANC than female; however, the differences were not statistically different (P > 0.05). The prevalence of neutropenia was lower in Saudi participants compared with non-Saudis. While the mean ANC was lower among Saudis as compared with non-Saudi participants. However, the differences were not statistically different (P > 0.05).
UNASSIGNED: This is the first study from the central region of Saudi Arabia that determined the prevalence of chronic benign neutropenia among healthy individuals. The prevalence of IBN was found to be relatively low. Furthermore, neutropenia was more frequent in males than females. Moreover, male neutropenic individuals have a lower ANC.
UNASSIGNED: This retrospective study analyzed complete blood count tests as part of routine checkups for chronic health conditions from April to September 2022. The 10,442 participants were randomly selected and their medical records were reviewed for neutropenia and mean absolute neutrophil counts (ANCs) were calculated. Descriptive analysis was employed to assess the prevalence of IBN across various demographic factors, such as age, gender, and nationality.
UNASSIGNED: The prevalence of IBN in the central region of Saudi Arabia was found to be 2.82% across the entire cohort of participants. The mean ANC among all participants was 4.55 × 109/L. The prevalence of neutropenia was higher in male participants compared with female. Male neutropenic had a lower mean ANC than female; however, the differences were not statistically different (P > 0.05). The prevalence of neutropenia was lower in Saudi participants compared with non-Saudis. While the mean ANC was lower among Saudis as compared with non-Saudi participants. However, the differences were not statistically different (P > 0.05).
UNASSIGNED: This is the first study from the central region of Saudi Arabia that determined the prevalence of chronic benign neutropenia among healthy individuals. The prevalence of IBN was found to be relatively low. Furthermore, neutropenia was more frequent in males than females. Moreover, male neutropenic individuals have a lower ANC.
摘要：
■中性粒细胞是循环中最常见的细胞类型，被认为是免疫系统抵抗微生物的第一道防线。这项研究旨在调查沙特阿拉伯中部地区健康个体中孤立的良性中性粒细胞减少症（IBN）的发生。
■这项回顾性研究分析了2022年4月至9月期间作为慢性健康状况常规检查的一部分的全血细胞计数检查。随机选择10,442名参与者，并审查他们的病历中的中性粒细胞减少症，并计算平均绝对中性粒细胞计数（ANC）。描述性分析用于评估IBN在各种人口统计学因素中的患病率，比如年龄,性别,和国籍。
■在整个参与者队列中，沙特阿拉伯中部地区的IBN患病率为2.82％。所有参与者的平均ANC为4.55×109/L。男性参与者中性粒细胞减少症的患病率高于女性。男性中性粒细胞减少症的平均ANC低于女性；然而，差异无统计学意义(P>0.05)。与非沙特人相比，沙特参与者的中性粒细胞减少症患病率较低。而与非沙特参与者相比，沙特人的平均非国大更低。然而,差异无统计学意义(P>0.05)。
■这是沙特阿拉伯中部地区的第一项研究，该研究确定了健康个体中慢性良性中性粒细胞减少症的患病率。发现IBN的患病率相对较低。此外，男性中性粒细胞减少症发生率高于女性.此外，男性中性粒细胞减少个体的ANC较低。
■这项回顾性研究分析了2022年4月至9月期间作为慢性健康状况常规检查的一部分的全血细胞计数检查。随机选择10,442名参与者，并审查他们的病历中的中性粒细胞减少症，并计算平均绝对中性粒细胞计数（ANC）。描述性分析用于评估IBN在各种人口统计学因素中的患病率，比如年龄,性别,和国籍。
■在整个参与者队列中，沙特阿拉伯中部地区的IBN患病率为2.82％。所有参与者的平均ANC为4.55×109/L。男性参与者中性粒细胞减少症的患病率高于女性。男性中性粒细胞减少症的平均ANC低于女性；然而，差异无统计学意义(P>0.05)。与非沙特人相比，沙特参与者的中性粒细胞减少症患病率较低。而与非沙特参与者相比，沙特人的平均非国大更低。然而,差异无统计学意义(P>0.05)。
■这是沙特阿拉伯中部地区的第一项研究，该研究确定了健康个体中慢性良性中性粒细胞减少症的患病率。发现IBN的患病率相对较低。此外，男性中性粒细胞减少症发生率高于女性.此外，男性中性粒细胞减少个体的ANC较低。
