PDF(Pubmed)
Abstract：
UNASSIGNED: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an inflammatory disorder of the CNS with a variety of clinical manifestations, including cerebral edema.
UNASSIGNED: A 7-year-old boy presented with headaches, nausea, and somnolence. He was found to have cerebral edema that progressed to brainstem herniation. Invasive multimodality neuromonitoring was initiated to guide management of intracranial hypertension and cerebral hypoxia while he received empiric therapies for neuroinflammation. Workup revealed serum myelin oligodendrocyte glycoprotein antibodies. He survived with a favorable neurologic outcome.
UNASSIGNED: We describe a child who presented with cerebral edema and was ultimately diagnosed with MOGAD. Much of his management was guided using data from invasive multimodality neuromonitoring. Invasive multimodality neuromonitoring may have utility in managing life-threatening cerebral edema due to neuroinflammation.
UNASSIGNED: A 7-year-old boy presented with headaches, nausea, and somnolence. He was found to have cerebral edema that progressed to brainstem herniation. Invasive multimodality neuromonitoring was initiated to guide management of intracranial hypertension and cerebral hypoxia while he received empiric therapies for neuroinflammation. Workup revealed serum myelin oligodendrocyte glycoprotein antibodies. He survived with a favorable neurologic outcome.
UNASSIGNED: We describe a child who presented with cerebral edema and was ultimately diagnosed with MOGAD. Much of his management was guided using data from invasive multimodality neuromonitoring. Invasive multimodality neuromonitoring may have utility in managing life-threatening cerebral edema due to neuroinflammation.
摘要：
■髓磷脂少突胶质细胞糖蛋白抗体相关疾病(MOGAD)是一种有多种临床表现的中枢神经系统炎症性疾病,包括脑水肿.
■一个7岁的男孩头痛，恶心,和嗜睡。他被发现患有脑水肿，进展为脑干疝。在接受经验性神经炎症治疗时，开始了有创多模态神经监测，以指导颅内高压和脑缺氧的管理。检查显示血清髓鞘少突胶质细胞糖蛋白抗体。他活了下来，神经结果良好。
■我们描述了一个出现脑水肿并最终被诊断为MOGAD的儿童。他的大部分管理都是使用来自侵入性多模态神经监测的数据进行指导的。侵入性多模态神经监测可能在管理由于神经炎症而危及生命的脑水肿方面具有实用性。
■一个7岁的男孩头痛，恶心,和嗜睡。他被发现患有脑水肿，进展为脑干疝。在接受经验性神经炎症治疗时，开始了有创多模态神经监测，以指导颅内高压和脑缺氧的管理。检查显示血清髓鞘少突胶质细胞糖蛋白抗体。他活了下来，神经结果良好。
■我们描述了一个出现脑水肿并最终被诊断为MOGAD的儿童。他的大部分管理都是使用来自侵入性多模态神经监测的数据进行指导的。侵入性多模态神经监测可能在管理由于神经炎症而危及生命的脑水肿方面具有实用性。
