UNASSIGNED: Pilomatrix carcinoma is uncommon and locally aggressive tumor of the hair follicle matrix. It is a malignant variant of pilomatricoma. If left untreated for a long time may attain massive size and has the potential for distant spread. Only few cases with brain extension have been reported in the literature. Diagnosis of these tumors is established by histopathology. Although pilomatrixoma and pilomatrix carcinoma are well-recognized lesions, clinically they are frequently misdiagnosed as other skin conditions. The tumors respond poorly to chemotherapy and radiotherapy. Thus, recommended treatment is a wide surgical excision with safe margins. Herein, we report the case of a 39-year-old African woman with pilomatrix carcinoma of the scalp eroding the skull bone with intracranial extension.
■毛囊基质癌是一种罕见的局部侵袭性毛囊基质肿瘤。它是毛囊瘤的恶性变体。如果长时间不处理,可能会达到巨大的尺寸,并有可能远距离传播。文献中仅报道了少数脑延伸的病例。这些肿瘤的诊断通过组织病理学确定。尽管毛囊瘤和毛囊瘤是公认的病变,在临床上,它们经常被误诊为其他皮肤疾病。肿瘤对化疗和放疗的反应较差。因此,推荐的治疗方法是具有安全切缘的广泛手术切除。在这里,我们报告了一例39岁的非洲妇女,头皮毛囊癌侵蚀颅骨并伴有颅内扩张。