PDF(Pubmed)
Abstract：
Prophylactic cranial irradiation (PCI) for limited disease small cell lung cancer is the standard of care for curative treatment of this disease. However, neurocognitive dysfunction is one of the late adverse events of PCI and is often problematic. Recently, hippocampal avoidance prophylactic cranial irradiation (HA-PCI) is sometimes performed to prevent neurocognitive dysfunction after PCI. In HA-PCI, the question is whether or not metastases appear around the hippocampus that were not irradiated. We have experienced a case of perihippocampal meningeal carcinomatosis after HA-PCI. We also draw attention to the potential risks of performing HA-PCI based on this experience.
摘要：
有限疾病小细胞肺癌的预防性颅骨照射（PCI）是治愈性治疗该疾病的标准护理。然而,神经认知功能障碍是PCI的晚期不良事件之一,并且通常是有问题的.最近,有时会进行海马回避预防性颅照射（HA-PCI）以预防PCI后的神经认知功能障碍。在HA-PCI中，问题是在未照射的海马周围是否出现转移。我们经历了1例HA-PCI术后海马周围脑膜癌。我们还提请注意根据这些经验进行HA-PCI的潜在风险。
