关键词: RS1 cyst-like degeneration intraretinal retinoschisin retinoschisis

Mesh : Humans Cats Animals Dogs Retinoschisis / veterinary complications pathology Retinal Detachment / veterinary complications pathology Retrospective Studies Retina / pathology Cat Diseases / pathology Dog Diseases / pathology

来  源:   DOI:10.1016/j.jcpa.2023.10.001

Abstract:
Retinoschisis is a poorly documented form of retinal degeneration characterized by cyst-like splitting that occurs between the inner nuclear and outer plexiform layers. The pathogenesis of retinoschisis is incompletely understood, but congenital, acquired and secondary aetiologies (glaucoma, inflammation, neoplasia) are described in humans. This retrospective study investigated the prevalence and associated histological and clinical features of retinoschisis in cats and dogs submitted for biopsy over a 10-year period. Of 140 samples with documented \'retinal vacuolation\', four out of 120 (3%) canine samples and one out of 20 (5%) feline samples had changes consistent with retinoschisis. In most cases (80%), there was concurrent retinal detachment. In cases with available histories, increased intraocular pressure, proptosis and retinal detachment were reported clinical findings. In cats and dogs, retinoschisis is a retinal change that is generally secondary to other ocular lesions.
摘要:
视网膜裂孔是一种记录较少的视网膜变性形式,其特征是在内核层和外丛状层之间发生囊肿样分裂。视网膜劈裂的发病机制尚不完全清楚,但是先天性的,获得性和继发性病因(青光眼,炎症,瘤形成)在人类中描述。这项回顾性研究调查了在10年内接受活检的猫和狗中视网膜裂孔的患病率以及相关的组织学和临床特征。在140个有记录的“视网膜空泡化”样本中,120例(3%)犬样本中的4例和20例(5%)猫样本中的1例具有与视网膜裂开一致的变化.在大多数情况下(80%),同时有视网膜脱离.在有可用历史记录的情况下,眼内压升高,报告了眼球突出和视网膜脱离的临床表现。在猫和狗中,视网膜劈裂是一种视网膜变化,通常继发于其他眼部病变。
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