Abstract：
BACKGROUND: During the Covid-19 pandemic, there has been a notable increase in self-medication with antibiotics or other medications due to impaired access to healthcare services. This kind of self-treatment, without comprehending the condition and its related risks, can result in misdiagnosis, overdosing and delaying in acquiring professional medical attention, or may even cause antimicrobial resistance. Additionally, reports have suggested that medical practitioners have prescribed medications inappropriately to patients with Covid-19. To investigate this further, this study compared the medications used by patients with Covid-19 prior to hospitalization with or without a medical recommendation.
METHODS: Data was extracted a mass survey of patients with of Covid-19 in Mashhad, and the patients were divided into two main groups: those who received medication with guidance from a medical professional (treatment group) and those who self-administered medications without professional oversight (self-treatment group). Statistical analysis was then conducted using SPSS version 26, the Chi-square, and multiple logistic regression test.
RESULTS: This study examined 3266 patients, with 1466 included in the analysis. Results showed that men (9.5 %), those living in rural areas (21 %), and those with no academic degree (37.5%) had a higher likelihood to self-medicating. Antibiotics were the most frequently used medications prior to hospitalization (9.5%). Comparing the two groups revealed that three drug categories- antibiotics, antivirals and other medications (medicines that are not in the other 4 main categories)- were utilized more often in the treatment group than in the self-treatment group, with a p-value of < 0.05. The only medical condition that had a significant difference between the two groups was diabetes, with 34.1 % in the self-treatment group versus 24.5 % in the treatment group (P < 0.05).
CONCLUSIONS: The Covid-19 pandemic has caused a surge in the inappropriate use of certain medications through self-medicating. This poses a serious risk to the health of patients, highlighting the need for not only adjusting guidelines but also raising awareness and enforcing compliance to prevent unnecessary use of drugs.
METHODS: Data was extracted a mass survey of patients with of Covid-19 in Mashhad, and the patients were divided into two main groups: those who received medication with guidance from a medical professional (treatment group) and those who self-administered medications without professional oversight (self-treatment group). Statistical analysis was then conducted using SPSS version 26, the Chi-square, and multiple logistic regression test.
RESULTS: This study examined 3266 patients, with 1466 included in the analysis. Results showed that men (9.5 %), those living in rural areas (21 %), and those with no academic degree (37.5%) had a higher likelihood to self-medicating. Antibiotics were the most frequently used medications prior to hospitalization (9.5%). Comparing the two groups revealed that three drug categories- antibiotics, antivirals and other medications (medicines that are not in the other 4 main categories)- were utilized more often in the treatment group than in the self-treatment group, with a p-value of < 0.05. The only medical condition that had a significant difference between the two groups was diabetes, with 34.1 % in the self-treatment group versus 24.5 % in the treatment group (P < 0.05).
CONCLUSIONS: The Covid-19 pandemic has caused a surge in the inappropriate use of certain medications through self-medicating. This poses a serious risk to the health of patients, highlighting the need for not only adjusting guidelines but also raising awareness and enforcing compliance to prevent unnecessary use of drugs.
摘要：
背景：在Covid-19大流行期间，由于无法获得医疗保健服务，使用抗生素或其他药物的自我药物治疗显着增加。这种自我治疗,在不了解病情及其相关风险的情况下，会导致误诊,过量服用和延迟获得专业医疗护理，甚至可能引起抗菌素耐药性。此外,有报道表明，医生给新冠肺炎患者开了不适当的药物处方。为了进一步调查，本研究比较了Covid-19患者住院前使用的药物,无论是否有医学建议.
方法：数据来自马什哈德Covid-19患者的大规模调查，患者分为两大类:在医学专业人员指导下接受药物治疗的患者(治疗组)和在没有专业监督的情况下自行用药的患者(自我治疗组).然后使用SPSS版本26进行统计分析，卡方，和多元Logistic回归检验。
结果：这项研究检查了3266名患者，分析中包括1466。结果显示，男性(9.5%)，生活在农村地区的人(21%)，没有学历的人(37.5%)自我用药的可能性更高。抗生素是住院前最常用的药物（9.5%）。比较两组，发现三种药物类别——抗生素，抗病毒药物和其他药物（不在其他4个主要类别的药物）-在治疗组比在自我治疗组使用更频繁，p值<0.05。两组之间唯一有显着差异的医疗状况是糖尿病，自我治疗组为34.1%，治疗组为24.5%（P<0.05）。
结论：新冠肺炎大流行通过自我用药导致某些药物的不当使用激增。这对患者的健康构成了严重的风险，强调不仅需要调整指导方针，而且需要提高认识和强制遵守，以防止不必要的药物使用。
方法：数据来自马什哈德Covid-19患者的大规模调查，患者分为两大类:在医学专业人员指导下接受药物治疗的患者(治疗组)和在没有专业监督的情况下自行用药的患者(自我治疗组).然后使用SPSS版本26进行统计分析，卡方，和多元Logistic回归检验。
结果：这项研究检查了3266名患者，分析中包括1466。结果显示，男性(9.5%)，生活在农村地区的人(21%)，没有学历的人(37.5%)自我用药的可能性更高。抗生素是住院前最常用的药物（9.5%）。比较两组，发现三种药物类别——抗生素，抗病毒药物和其他药物（不在其他4个主要类别的药物）-在治疗组比在自我治疗组使用更频繁，p值<0.05。两组之间唯一有显着差异的医疗状况是糖尿病，自我治疗组为34.1%，治疗组为24.5%（P<0.05）。
结论：新冠肺炎大流行通过自我用药导致某些药物的不当使用激增。这对患者的健康构成了严重的风险，强调不仅需要调整指导方针，而且需要提高认识和强制遵守，以防止不必要的药物使用。
