Abstract:
Cefiderocol is a novel cephalosporin antibiotic with activity against multidrug-resistant Gram-negative bacteria and limited pediatric experience. This case series describes 3 immunocompromised children receiving blood transfusion who developed benign red or purple urine with administration of cefiderocol. Interaction with iron from blood products is a possible mechanism. It is important to recognize this phenomenon and distinguish it from hematuria to avoid unnecessary diagnostic testing.
摘要:
头孢地洛是一种新型头孢菌素类抗生素,具有抗多重耐药革兰氏阴性菌的活性,儿科经验有限。本病例系列描述了3名接受输血的免疫功能低下的儿童,他们在服用头孢地洛后出现良性红色或紫色尿液。与血液制品中的铁相互作用是一种可能的机制。重要的是要认识到这种现象,并将其与血尿区分开来,以避免不必要的诊断测试。