PDF(Pubmed)
Abstract：
UNASSIGNED: The study aimed to collect and compare clinical and laboratory findings of children with severe and nonsevere COVID-19 in Kermanshah City, located in the west of Iran.
UNASSIGNED: The study was conducted on 500 children with COVID-19 hospitalized in Mohammad-Kermanshahi Hospital in Kermanshah City. Pediatric COVID-19 was confirmed by reverse transcription-polymerase chain reaction (RT-PCR) test using respiratory secretion samples. Medical records were reviewed and information related to demographic characteristics, underlying diseases, clinical manifestations, laboratory findings, and chest computed tomography (CT) scans were all extracted from electronic and paper records. Patients were divided into three groups according to the severity of the disease: mild, moderate, and severe. Clinical and laboratory findings were compared between the groups and the collected data were analyzed by statistical methods.
UNASSIGNED: Out of 500 patients, 286 were boys and 214 were girls. Of the patients, 321 cases were only COVID-19, while 179 patients were diagnosed as Multisystem Inflammatory Syndrome in Children (MIS-C) positive. The average age of COVID-19 patients was 3.85 ± 4.48 and of MIS-C patients was 3.1 ± 3.5. In order, fever, cough, and heart disorders were the most common symptoms in patients with COVID-19 and MIS-C, respectively. In terms of disease severity, 246 patients had mild disease, 19 patients had moderate disease, and 56 patients had severe disease. In severe patients, the average number of white blood cells (WBC) was higher, while the average number of lymphocytes was lower. Also, in these patients, the average age was lower, and most of them had respiratory distress. In mild patients, often cough, diarrhea, and vomiting were observed.
UNASSIGNED: The results of our study showed that laboratory factors such as WBC count, lymphocyte count, CT findings, Respiratory distress, cough, diarrhea, and vomiting can be used to evaluate the severity of COVID-19 in children.
UNASSIGNED: The study was conducted on 500 children with COVID-19 hospitalized in Mohammad-Kermanshahi Hospital in Kermanshah City. Pediatric COVID-19 was confirmed by reverse transcription-polymerase chain reaction (RT-PCR) test using respiratory secretion samples. Medical records were reviewed and information related to demographic characteristics, underlying diseases, clinical manifestations, laboratory findings, and chest computed tomography (CT) scans were all extracted from electronic and paper records. Patients were divided into three groups according to the severity of the disease: mild, moderate, and severe. Clinical and laboratory findings were compared between the groups and the collected data were analyzed by statistical methods.
UNASSIGNED: Out of 500 patients, 286 were boys and 214 were girls. Of the patients, 321 cases were only COVID-19, while 179 patients were diagnosed as Multisystem Inflammatory Syndrome in Children (MIS-C) positive. The average age of COVID-19 patients was 3.85 ± 4.48 and of MIS-C patients was 3.1 ± 3.5. In order, fever, cough, and heart disorders were the most common symptoms in patients with COVID-19 and MIS-C, respectively. In terms of disease severity, 246 patients had mild disease, 19 patients had moderate disease, and 56 patients had severe disease. In severe patients, the average number of white blood cells (WBC) was higher, while the average number of lymphocytes was lower. Also, in these patients, the average age was lower, and most of them had respiratory distress. In mild patients, often cough, diarrhea, and vomiting were observed.
UNASSIGNED: The results of our study showed that laboratory factors such as WBC count, lymphocyte count, CT findings, Respiratory distress, cough, diarrhea, and vomiting can be used to evaluate the severity of COVID-19 in children.
摘要：
■该研究旨在收集和比较克尔曼沙市重度和非重度COVID-19儿童的临床和实验室检查结果，位于伊朗西部。
这项研究是对在克尔曼沙赫市的穆罕默德-克尔曼沙希医院住院的500名COVID-19儿童进行的。儿科COVID-19通过使用呼吸道分泌物样本的逆转录-聚合酶链反应(RT-PCR)测试得到证实。对医疗记录进行审查，并提供与人口统计学特征相关的信息，潜在的疾病，临床表现，实验室发现,和胸部计算机断层扫描（CT）扫描均从电子和纸质记录中提取。根据疾病的严重程度将患者分为三组：轻度，中度,和严重。组间比较临床和实验室检查结果，并通过统计学方法对收集的数据进行分析。
■在500名患者中，286人是男孩，214人是女孩。在患者中，321例仅COVID-19，而179例诊断为儿童多系统炎症综合征（MIS-C）阳性。COVID-19患者的平均年龄为3.85±4.48，MIS-C患者的平均年龄为3.1±3.5。为了,发烧,咳嗽,心脏病是COVID-19和MIS-C患者最常见的症状，分别。就疾病的严重程度而言,246名患者患有轻度疾病，19例患者患有中度疾病，56名患者患有严重疾病。在重症患者中，白细胞（WBC）的平均数量较高，而淋巴细胞的平均数量较低。此外，在这些患者中，平均年龄较低，他们中的大多数都有呼吸窘迫。在轻度患者中，经常咳嗽,腹泻,观察到呕吐。
■我们的研究结果表明，实验室因素，如白细胞计数，淋巴细胞计数,CT检查结果,呼吸窘迫,咳嗽,腹泻,呕吐可用于评估儿童COVID-19的严重程度。
这项研究是对在克尔曼沙赫市的穆罕默德-克尔曼沙希医院住院的500名COVID-19儿童进行的。儿科COVID-19通过使用呼吸道分泌物样本的逆转录-聚合酶链反应(RT-PCR)测试得到证实。对医疗记录进行审查，并提供与人口统计学特征相关的信息，潜在的疾病，临床表现，实验室发现,和胸部计算机断层扫描（CT）扫描均从电子和纸质记录中提取。根据疾病的严重程度将患者分为三组：轻度，中度,和严重。组间比较临床和实验室检查结果，并通过统计学方法对收集的数据进行分析。
■在500名患者中，286人是男孩，214人是女孩。在患者中，321例仅COVID-19，而179例诊断为儿童多系统炎症综合征（MIS-C）阳性。COVID-19患者的平均年龄为3.85±4.48，MIS-C患者的平均年龄为3.1±3.5。为了,发烧,咳嗽,心脏病是COVID-19和MIS-C患者最常见的症状，分别。就疾病的严重程度而言,246名患者患有轻度疾病，19例患者患有中度疾病，56名患者患有严重疾病。在重症患者中，白细胞（WBC）的平均数量较高，而淋巴细胞的平均数量较低。此外，在这些患者中，平均年龄较低，他们中的大多数都有呼吸窘迫。在轻度患者中，经常咳嗽,腹泻,观察到呕吐。
■我们的研究结果表明，实验室因素，如白细胞计数，淋巴细胞计数,CT检查结果,呼吸窘迫,咳嗽,腹泻,呕吐可用于评估儿童COVID-19的严重程度。
