OBJECTIVE: The present study aimed to assess LV volume and function in the third trimester of a healthy pregnancy using 4DE and to compare the results of LV assessment using 4DE with those of LV assessment using conventional two-dimensional (2D) echocardiography.
METHODS: The study was conducted on 75 healthy pregnant women (the case group) and 75 non-pregnant women (the control group). The participants attended Al-Fortat Teaching Hospital from April 1, 2022, to May 30, 2023, and had 2D and 4D echocardiographic studies performed on them.
RESULTS: The LV end-diastolic volume (EDV), end-systolic volume (ESV), and cardiac output (CO) were significantly increased in the case group compared to the control group (90.87 ± 18.03 ml vs. 62.64 ± 14.11 ml, P<0.001; 35.59 ± 6.52 ml vs. 22.42 ± 5.82 ml, P<0.001; and 4.87 ± 1.27 vs. 3.35 ± 0.87 L/m, P<0.001, respectively). In contrast, the LV ejection fraction (LVEF) was significantly decreased in the pregnant group compared to the control group (60.37 ± 5.42 % vs. 64.04 ± 4.99 %, P<0.01). Additionally, the study showed significant differences in EDV, ESV, ejection fraction (EF%), and CO (P<0.001) between 2D and 4D echocardiography, according to the Bland Altman test.
CONCLUSIONS: In healthy pregnant women in their third trimester, there is an increase in the indicators of preload (ventricular volume and CO) and a decrease in EF%. The 4DE provides detailed images and information about cardiac volumes and function, allowing for the early detection of any potential problems that may arise during pregnancy and thus improving the health outcomes of both the mother and the developing fetus.
目的:本研究旨在使用4DE评估健康妊娠晚期的LV体积和功能,并将使用4DE评估LV的结果与使用常规二维(2D)超声心动图评估LV的结果进行比较。
方法:本研究对75例健康孕妇(病例组)和75例非孕妇(对照组)进行了研究。参与者于2022年4月1日至2023年5月30日在Al-Fortat教学医院就诊,并对其进行了2D和4D超声心动图研究。
结果:左心室舒张末期容积(EDV),收缩末期容积(ESV),与对照组相比,病例组和心输出量(CO)显着增加(90.87±18.03mlvs.62.64±14.11ml,P<0.001;35.59±6.52mlvs.22.42±5.82ml,P<0.001;4.87±1.27vs.3.35±0.87L/m,分别为P<0.001)。相比之下,与对照组相比,妊娠组的LV射血分数(LVEF)显着降低(60.37±5.42%vs.64.04±4.99%,P<0.01)。此外,研究表明,EDV存在显著差异,ESV,射血分数(EF%),2D和4D超声心动图之间的CO(P<0.001),根据BlandAltman的测试.
结论:在妊娠晚期的健康孕妇中,前负荷指标(心室容积和CO)增加,EF%降低。4DE提供有关心脏容积和功能的详细图像和信息,允许早期发现怀孕期间可能出现的任何潜在问题,从而改善母亲和发育中的胎儿的健康结果。