关键词: Parotid gland adenolymphoma

Mesh : Humans Adenolymphoma / pathology surgery Parotid Neoplasms / pathology surgery Retrospective Studies Female Male England / epidemiology Middle Aged Aged Parotid Gland / pathology surgery

来  源:   DOI:10.1017/S0022215123001834

Abstract:
OBJECTIVE: Warthin\'s tumours are the second most common benign parotid tumours in the UK. The World Health Organization states that 5-14 per cent of patients have bilateral Warthin\'s tumours. This study aimed to: assess the presence of contralateral Warthin\'s tumours in patients who underwent surgery over the past 16 years at a head and neck unit in England, and perform the first systematic literature review on bilateral Warthin\'s tumours.
METHODS: A retrospective analysis was conducted on patients diagnosed with Warthin\'s tumour based on histology between 2005 and 2020. Additionally, a systematic review (International Prospective Register of Systematic Reviews (\'PROSPERO\') registration number: CRD42022326846) was performed using PubMed and the Cochrane Library.
RESULTS: Among 290 patients diagnosed with Warthin\'s tumours based on histology following surgery, 24.5 per cent had bilateral Warthin\'s tumours. The systematic review identified 157 papers, with 14 meeting the inclusion criteria.
CONCLUSIONS: This study revealed that 24.5 per cent of patients had bilateral Warthin\'s tumours, deviating from the suggested range. These findings are of interest to surgeons discussing the disease with patients.
摘要:
目的:Warthin的肿瘤是英国第二常见的良性腮腺肿瘤。世界卫生组织指出,5-14%的患者患有双侧Warthin肿瘤。这项研究旨在:评估在过去16年中在英格兰头颈部接受手术的患者对侧Warthin肿瘤的存在,并对双侧Warthin肿瘤进行了首次系统的文献综述。
方法:对2005年至2020年诊断为Warthin肿瘤的患者进行回顾性分析。此外,使用PubMed和Cochrane图书馆进行了系统评价(国际前瞻性系统评价登记册(\'PROSPERO\')注册号:CRD420223226846)。
结果:在手术后根据组织学诊断为Warthin肿瘤的290例患者中,24.5%患有双侧Warthin肿瘤。系统审查确定了157篇论文,14人符合纳入标准。
结论:这项研究显示,24.5%的患者患有双侧Warthin肿瘤,偏离建议范围。这些发现对外科医生与患者讨论该疾病很有兴趣。
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