Abstract：
Biomaterial scientists have recently focused their attention on evaluating various aspects of delivering genetic materials into cells to induce a cellular response. The process involves complexing negatively charged plasmids, followed by delivering the resulting package into cells, a process facilitated by lipids, peptides, viruses, synthetically modified cationic polymers, and specific inorganic nanomaterials. In the context of gene delivery for specific imaging in biological and biomedical applications, fluorescence nanocrystals or quantum dots (QDs) present promising candidates as engineered nanoparticles (NPs). This literature review study aims to investigate the potential of QDs as a novel tool for gene delivery to retinal cells. The proficiency of QDs in this context arises from their unique physicochemical characteristics, including optical electronic and catalytic properties, which render them viable options for biosensing imaging, drug delivery, and gene delivery applications. In the field of gene delivery to the retinal cells, factors such as photoluminescence, quantum yield, biocompatibility, size, and shape play crucial roles in the utilization of QDs. In this paper, we discuss the most appropriate credentials and briefly outline the findings, supported by relevant illustrative samples, to explore the delivery of genetic material utilizing QDs.
摘要：
生物材料科学家最近将注意力集中在评估将遗传物质递送到细胞中以诱导细胞反应的各个方面。该过程涉及络合带负电荷的质粒，然后将产生的包装放入细胞中，由脂质促进的过程，肽，病毒,合成改性阳离子聚合物，和特定的无机纳米材料。在生物和生物医学应用中用于特定成像的基因递送的背景下，荧光纳米晶体或量子点（QD）提出了有希望的候选工程纳米粒子（NP）。本文献综述研究旨在研究量子点作为基因传递到视网膜细胞的新工具的潜力。量子点在这种情况下的熟练程度源于其独特的物理化学特性，包括光电和催化性能，这使它们成为生物传感成像的可行选择，药物输送,和基因递送应用。在基因传递给视网膜细胞的领域，如光致发光等因素，量子产率，生物相容性，尺寸,和形状在量子点的利用中起着至关重要的作用。在本文中,我们讨论了最合适的证书，并简要概述了调查结果，由相关的说明性样本支持，探索利用量子点传递遗传物质。
