关键词: Catatonia Chronic intestinal pseudo-obstruction Gamma-aminobutyric acid Lorazepam Schizophrenia Treatment

来  源:   DOI:10.1016/j.heliyon.2023.e21067   PDF(Pubmed)

Abstract:
It is challenging to manage schizophrenic catatonia and comorbid chronic intestinal pseudo-obstruction (CIPO). The pathology of catatonia is unclear. There are few reports or research on this issue. In this case, we present a middle-aged woman diagnosed with schizophrenia with catatonic features and comorbid CIPO. In the treatment process, modified electroconvulsive therapy (mECT) improved her stupor and CIPO partially. Lorazepam alleviated her stupor and CIPO completely. It is the first report describing complete remission with lorazepam in patient suffering from comorbid schizophrenic catatonia and CIPO, which may benefit the exploration of pathophysiology and treatment of comorbidity of schizophrenia with catatonia and CIPO.
摘要:
治疗精神分裂症性紧张症和慢性肠道假性梗阻(CIPO)具有挑战性。紧张症的病理尚不清楚。关于这个问题的报道或研究很少。在这种情况下,我们介绍了一名诊断为精神分裂症的中年女性,其具有紧张性特征和合并症CIPO。在治疗过程中,改良电惊厥疗法(mECT)部分改善了她的昏迷和CIPO。劳拉西泮完全减轻了她的昏迷和CIPO。这是第一份描述劳拉西m在患有精神分裂症合并症和CIPO的患者中完全缓解的报告,这可能有助于探索精神分裂症伴紧张症和CIPO合并症的病理生理学和治疗。
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