PDF(Pubmed)
Abstract：
The concentration of intramuscular fat (IMF) is a crucial determinant of yak meat quality. However, the molecular mechanisms that regulate IMF in yak remain largely elusive. In our study, we conducted transcriptome sequencing on the longissimus dorsi muscle tissues of yaks with varying IMF contents. We then filtered differentially expressed genes (DEGs), microRNAs (DEMs), and long non-coding RNAs (DELs) to elucidate potential regulatory pathways of adipogenesis in yaks. Overall, our research sheds light on an array of potential mRNAs and noncoding RNAs implicated in IMF deposition and elaborates on the role of HIF1α in yaks. These findings contribute valuable insights that can serve as a guide for further research into the molecular mechanisms governing IMF deposition.
摘要：
肌内脂肪（IMF）的浓度是牦牛肉品质的关键决定因素。然而,调节牦牛IMF的分子机制在很大程度上仍然难以捉摸。在我们的研究中,我们对IMF含量不同的牦牛背肌组织进行了转录组测序。然后我们过滤了差异表达基因（DEG），microRNAs(DEM),和长链非编码RNA（DEL）阐明牦牛脂肪生成的潜在调控途径。总的来说,我们的研究揭示了一系列与IMF沉积有关的潜在mRNA和非编码RNA，并阐述了HIF1α在牦牛中的作用。这些发现提供了宝贵的见解，可以作为进一步研究控制IMF沉积的分子机制的指南。
