PDF(Pubmed)
Abstract：
UNASSIGNED: To report a case of recurrent retinoblastoma following transpupillary thermotherapy (TTT) with development of scleral ectasia, as well as their successful treatment with intra-arterial chemotherapy.
UNASSIGNED: A 15-month-old girl with bilateral retinoblastoma presented with recurrent retinoblastoma and associated scleral ectasia with concern for extraocular extension after receiving multiple round of systemic chemotherapy and TTT. Given her negative systemic evaluation, decision was made to pursue intra-arterial chemotherapy. After completion of six rounds of 3-agent intra-arterial chemotherapy, the recurrent retinoblastoma had completely regressed and the scleral ectasia had improved and fibrosed.
UNASSIGNED: The sclera is classically viewed as hyperthermy-resistant to TTT. Here, we describe scleral ectasia due to aggressive TTT with recurrence of the retinoblastoma. Our treatment with intra-arterial chemotherapy not only caused complete regression of the recurrent retinoblastoma, but it also contributed to the stabilization and improvement of the weakened scleral.
UNASSIGNED: A 15-month-old girl with bilateral retinoblastoma presented with recurrent retinoblastoma and associated scleral ectasia with concern for extraocular extension after receiving multiple round of systemic chemotherapy and TTT. Given her negative systemic evaluation, decision was made to pursue intra-arterial chemotherapy. After completion of six rounds of 3-agent intra-arterial chemotherapy, the recurrent retinoblastoma had completely regressed and the scleral ectasia had improved and fibrosed.
UNASSIGNED: The sclera is classically viewed as hyperthermy-resistant to TTT. Here, we describe scleral ectasia due to aggressive TTT with recurrence of the retinoblastoma. Our treatment with intra-arterial chemotherapy not only caused complete regression of the recurrent retinoblastoma, but it also contributed to the stabilization and improvement of the weakened scleral.
摘要：
■报告一例经瞳孔热疗（TTT）并发展为巩膜扩张后复发性视网膜母细胞瘤，以及动脉内化疗的成功治疗。
■一名患有双侧视网膜母细胞瘤的15个月大女孩在接受多轮全身化疗和TTT后，出现复发性视网膜母细胞瘤和相关巩膜扩张，并担心眼外扩张。鉴于她的负面系统评价，决定进行动脉内化疗.在完成六轮三剂动脉内化疗后，复发性视网膜母细胞瘤完全消退,巩膜扩张改善并纤维化.
■巩膜通常被认为对TTT具有抗高温作用。这里,我们描述了由侵袭性TTT引起的巩膜扩张伴视网膜母细胞瘤复发.我们的动脉内化疗治疗不仅导致复发性视网膜母细胞瘤完全消退，但它也有助于巩膜弱化的稳定和改善。
■一名患有双侧视网膜母细胞瘤的15个月大女孩在接受多轮全身化疗和TTT后，出现复发性视网膜母细胞瘤和相关巩膜扩张，并担心眼外扩张。鉴于她的负面系统评价，决定进行动脉内化疗.在完成六轮三剂动脉内化疗后，复发性视网膜母细胞瘤完全消退,巩膜扩张改善并纤维化.
■巩膜通常被认为对TTT具有抗高温作用。这里,我们描述了由侵袭性TTT引起的巩膜扩张伴视网膜母细胞瘤复发.我们的动脉内化疗治疗不仅导致复发性视网膜母细胞瘤完全消退，但它也有助于巩膜弱化的稳定和改善。
