PDF(Pubmed)
Abstract：
UNASSIGNED: Guillain-Barré syndrome (GBS) is an acute inflammatory disease of the peripheral nervous system, rarely following Varicella-zoster virus (VZV) infection. The authors aimed to review all cases in the English literature of GBS that occurred after primary VZV infection to investigate the clinical features, diagnostic workup, treatment, and outcome of patients with GBS following VZV.
UNASSIGNED: PubMed, Scopus, and Embase are systematically searched from their inception to 9 May 2022 to collect all cases of GBS following varicella-zoster infection. Patients with GBS following VZV reactivation were excluded.
UNASSIGNED: Among the 29 patients, the age of presentation ranged from 1.5 to 70 years with a median of 37, with a yield for males (81.5%). Most of the patients presented with sensory-motor symptoms (65.4%) and suffered from tetraparesis (81.5%). Cranial nerve palsy was present in (84%) of patients, and the seventh cranial nerve was the most commonly affected nerve (75%). Lumbar puncture showed albuminocytological dissociation in (80%) of patients. The dominant nerve conduction study subtype was acute inflammatory demyelinating polyneuropathy (65.3%). in addition, the magnetic resonance imaging showed pathological findings in only (47.5%) of the patients. Intravenous immunoglobulin is now the drug of choice for all cases of GBS following VZV infection.
UNASSIGNED: GBS is a rare neurological complication of primary infection with VZV. However, the authors should suspect this syndrome when a patient develops ascending weakness, regardless of the absence of areflexia and albuminocytological dissociation. Drug therapy with IIVIg ensures a gradual improvement for the patient over a period of weeks to several months.
UNASSIGNED: PubMed, Scopus, and Embase are systematically searched from their inception to 9 May 2022 to collect all cases of GBS following varicella-zoster infection. Patients with GBS following VZV reactivation were excluded.
UNASSIGNED: Among the 29 patients, the age of presentation ranged from 1.5 to 70 years with a median of 37, with a yield for males (81.5%). Most of the patients presented with sensory-motor symptoms (65.4%) and suffered from tetraparesis (81.5%). Cranial nerve palsy was present in (84%) of patients, and the seventh cranial nerve was the most commonly affected nerve (75%). Lumbar puncture showed albuminocytological dissociation in (80%) of patients. The dominant nerve conduction study subtype was acute inflammatory demyelinating polyneuropathy (65.3%). in addition, the magnetic resonance imaging showed pathological findings in only (47.5%) of the patients. Intravenous immunoglobulin is now the drug of choice for all cases of GBS following VZV infection.
UNASSIGNED: GBS is a rare neurological complication of primary infection with VZV. However, the authors should suspect this syndrome when a patient develops ascending weakness, regardless of the absence of areflexia and albuminocytological dissociation. Drug therapy with IIVIg ensures a gradual improvement for the patient over a period of weeks to several months.
摘要：
■格林-巴利综合征（GBS）是一种周围神经系统的急性炎症性疾病，很少发生水痘-带状疱疹病毒（VZV）感染。作者旨在回顾原发性VZV感染后发生的GBS的英文文献中的所有病例，以探讨其临床特征。诊断检查,治疗,以及VZV后GBS患者的预后。
■PubMed,Scopus,从开始到2022年5月9日，对Embase进行了系统搜索，以收集水痘-带状疱疹感染后的所有GBS病例。排除VZV再激活后的GBS患者。
■在29名患者中，就诊年龄为1.5~70岁,中位数为37岁,男性产量为81.5%.大多数患者表现为感觉运动症状（65.4％）和四轻瘫（81.5％）。（84%）的患者出现颅神经麻痹，第七脑神经是最常见的神经（75％）。腰椎穿刺显示（80％）患者的白蛋白细胞解离。显性神经传导研究亚型为急性炎性脱髓鞘性多发性神经病(65.3%)。此外,磁共振成像仅显示(47.5%)患者的病理结果.静脉免疫球蛋白现在是VZV感染后所有GBS病例的首选药物。
■GBS是VZV原发感染的罕见神经系统并发症。然而,当患者出现上升无力时，作者应该怀疑这种综合征，无论无反射和白蛋白细胞解离。使用IIVIg的药物治疗确保患者在数周至数月的时间内逐渐改善。
■PubMed,Scopus,从开始到2022年5月9日，对Embase进行了系统搜索，以收集水痘-带状疱疹感染后的所有GBS病例。排除VZV再激活后的GBS患者。
■在29名患者中，就诊年龄为1.5~70岁,中位数为37岁,男性产量为81.5%.大多数患者表现为感觉运动症状（65.4％）和四轻瘫（81.5％）。（84%）的患者出现颅神经麻痹，第七脑神经是最常见的神经（75％）。腰椎穿刺显示（80％）患者的白蛋白细胞解离。显性神经传导研究亚型为急性炎性脱髓鞘性多发性神经病(65.3%)。此外,磁共振成像仅显示(47.5%)患者的病理结果.静脉免疫球蛋白现在是VZV感染后所有GBS病例的首选药物。
■GBS是VZV原发感染的罕见神经系统并发症。然而,当患者出现上升无力时，作者应该怀疑这种综合征，无论无反射和白蛋白细胞解离。使用IIVIg的药物治疗确保患者在数周至数月的时间内逐渐改善。
