PDF(Pubmed)
Abstract：
This study analyzed the effect of China\'s fluorosis prevention and control program, which has been in effect for more than 40 years, and the impact of fluorosis on children\'s health. Relevant research studies were retrieved from the following online databases from the time of their inception to May 2022: PubMed, ScienceDirect, Embase, Cochrane, China National Knowledge Infrastructure, and Wanfang. The Review Manager 5.3 software was used in statistical analyses. This article included seventy studies: Thirty-eight studies reported the effect of improving water quality and reducing fluoride content, the incidence rate of dental fluorosis in children, and the level of urinary fluoride, and thirty-two studies reported the intelligence quotient (IQ) and health status of children. Following water improvement strategies, the fluoride levels in drinking water decreased significantly; urinary fluoride levels and dental fluorosis decreased significantly in children. With regard to the effect of fluorosis on the IQ of children, the results showed that the IQ of children in areas with a high fluoride of fluorosis was lesser than that in areas with a low fluoride, and this difference was significant. Based on the prevalence of dental fluorosis and its effect on the intelligence of children, it appears that reducing fluoride levels in drinking water and monitoring water quality are important strategies for the prevention and treatment of fluorosis.
摘要：
本研究分析了我国氟中毒防治方案的效果,已经生效了40多年，以及氟中毒对儿童健康的影响。从成立到2022年5月的以下在线数据库中检索了相关研究：PubMed，ScienceDirect,Embase,科克伦,中国国家知识基础设施，还有万方。在统计分析中使用ReviewManager5.3软件。本文包括70项研究：38项研究报告了改善水质和降低氟化物含量的效果，儿童氟斑牙的发病率，和尿中氟化物的水平，32项研究报告了儿童的智商（IQ）和健康状况。遵循水改善策略，饮用水中的氟化物水平显着下降；儿童的尿氟化物水平和氟斑牙显着下降。关于氟中毒对儿童智商的影响，结果表明，氟中毒高氟地区儿童的智商低于低氟地区，这种差异是显著的。基于氟斑牙的患病率及其对儿童智力的影响，看来，降低饮用水中的氟化物含量和监测水质是预防和治疗氟中毒的重要策略。
