关键词: Cardiovascular complications Infective Endocarditis Outcome Stress cardiomyopathy Termination of pregnancy

来  源:   DOI:10.4330/wjc.v15.i10.518   PDF(Pubmed)

Abstract:
BACKGROUND: Around 1 million cases of medical termination of pregnancy (MTP) take place yearly in the United States of America with around 2 percent of this population developing complications. The cardiovascular (CVD) complications occurring post MTP or after stillbirth is not very well described.
OBJECTIVE: To help the reader better understand, prepare, and manage these complications by reviewing various cardiac comorbidities seen after MTP.
METHODS: We performed a literature search in PubMed, Medline, RCA, and google scholar, using the search terms \"abortions\" or \"medical/legal termination of pregnancy\" and \"cardiac complications\" or \"cardiovascular complications\".
RESULTS: The most common complications described in the literature following MTP were infective endocarditis (IE) (n = 16), takotsubo cardiomyopathy (TTC) (n = 7), arrhythmias (n = 5), and sudden coronary artery dissection (SCAD) (n = 4). The most common valve involved in IE was the tricuspid valve in 69% (n = 10). The most observed causative organism was group B Streptococcus in 81% (n = 12). The most common type of TTC was apical type in 57% (n = 4). Out of five patients developing arrhythmia, bradycardia was the most common and was seen in 60% (3/5) of the patients. All four cases of SCAD-P type presented as acute coronary syndrome 10-14 d post termination of pregnancy with predominant involvement of the right coronary artery. Mortality was only reported following IE in 6.25%. Clinical recovery was reported consistently after optimal medical management following all these complications.
CONCLUSIONS: In conclusion, the occurrence of CVD complications following pregnancy termination is infrequently documented in the existing literature. In this review, the most common CVD complication following MTP was noted to be IE and TTC.
摘要:
背景:在美国,每年约有100万例医疗终止妊娠(MTP),其中约2%的人群出现并发症。MTP后或死产后发生的心血管(CVD)并发症没有得到很好的描述。
目的:为了帮助读者更好地理解,准备,并通过回顾MTP后发现的各种心脏合并症来管理这些并发症。
方法:我们在PubMed,Medline,RCA,和谷歌学者,使用搜索字词“流产”或“医疗/合法终止妊娠”和“心脏并发症”或“心血管并发症”。
结果:文献中描述的MTP后最常见的并发症是感染性心内膜炎(IE)(n=16),Takotsubo心肌病(TTC)(n=7),心律失常(n=5),和突发性冠状动脉夹层(SCAD)(n=4)。IE中最常见的瓣膜是三尖瓣,占69%(n=10)。观察到的病原体最多的是B组链球菌,占81%(n=12)。最常见的TTC类型为顶型,占57%(n=4)。在五名出现心律失常的患者中,心动过缓是最常见的,在60%(3/5)的患者中可见。所有4例SCAD-P型病例在终止妊娠后10-14d表现为急性冠状动脉综合征,主要累及右冠状动脉。仅在IE后报告死亡率为6.25%。在所有这些并发症发生后,经过最佳医疗管理后,临床恢复得到一致报告。
结论:结论:在现有文献中,妊娠终止后CVD并发症的发生并不常见.在这次审查中,MTP后最常见的CVD并发症是IE和TTC.
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